Neutral tagging and detailed analysis of bacterial growth kinetics can quantify the mechanisms of colonization resistance in differently colonized animals.
PTBP2 ensures that adult protein variants are expressed only in mature neurons through regulation of alternative splicing during early neuronal development.
The utilization of hydrogen/deuterium exchange mass spectrometry reveals dynamic insights and interactions driving liquid-liquid demixing of the chromosome passenger complex.
Anthony J Linares, Chia-Ho Lin ... Douglas L Black
The RNA binding protein PTBP1 controls an extensive program of alternative splicing in embryonic stem cells, one function of which is to repress neuronal transcriptional programs.
Somsakul Pop Wongpalee, Ajay Vashisht ... Douglas L Black
A protein regulator of alternative pre-mRNA splicing arrests spliceosome assembly at a previously unrecognized step that defines new intermediate stages in the formation of exon complexes.
Michael N Economo, Nathan G Clack ... Jayaram Chandrashekar
High-resolution fluorescence imaging of the complete mouse brain enables many neurons to be efficiently visualized in their entirety, revealing all targets of neurons that project widely across the brain.