The modelled structure of a membrane protein supports the hypothesis that it has a new fold with a channel that allows a chemical group to cross the membrane to decorate surface structures.

PP1-Bud14 is a novel Spindle Position Checkpoint component.

Direct- and indirect pathway neurons of the posterior striatum display divergent in vivo and ex vivo plasticity after fear learning, and differentially modulate defensive behaviors displayed in the presence, and absence of threat-predicting sensory cues.

A modelling-based analysis reveals a novel type of selectivity for chromatic contrast in a mouse retinal ganglion cell type, and experimental evidence shows that this feature makes this cell type well suited for detecting behaviourally relevant changes in visual context.

Combined experimental and theoretical analysis identifies a molecular mechanism akin to working memory that enables single cells to perform complex navigation tasks in changing growth factor fields, beyond simple stimulus-response associations.

The neuronal glutamate transporter EAAC1 limits excitation and lateral inhibition between D1-MSNs, which are important for the execution of slow-switching flexible behaviors.

Dorsal raphe Pet1 neurons are molecularly heterogeneous, comprising as many as fourteen distinct subtypes that show biased cell body distributions across dorsal raphe subdomains.

A phase transition of TIR-1/SARM1 induced by either pathogen or non-pathogen stress potentiates its intrinsic NADase activity, which activates the p38 PMK-1 signaling cascade to induce protective immune defenses in Caenorhabditis elegans intestinal epithelial cells.