179 results found
    1. Cell Biology

    SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus

    Dandan Wu, Chi Yang ... Zhenhong Zhuang
    Chromatin immunoprecipitation sequencing and RNA sequencing have elucidated the complex transcript regulation pathways orchestrated by SntB, pivotal for Aspergillus flavus's development, mycotoxin production, and virulence.
    1. Cell Biology
    2. Neuroscience

    Synaptotagmin 1 directs repetitive release by coupling vesicle exocytosis to the Rab3 cycle

    Yunsheng Cheng, Jiaming Wang ... Mei Ding
    Experiments in C. elegans reveal how synaptotagmin and Rab3, the 'yin and yang' of synapses, control whether transmitter vesicles remain docked at the presynaptic membrane or release their contents into the synapse.
    1. Computational and Systems Biology
    2. Medicine

    The vaginal immunoproteome for the prediction of spontaneous preterm birth: A retrospective longitudinal study

    Zachary Shaffer, Roberto Romero ... Nardhy Gomez-Lopez
    The vaginal immunoproteome in pregnancy is more predictive of spontaneous preterm birth (sPTB) than maternal characteristics alone, with sPTB cases showing heightened pro-inflammatory profiles accompanied by reduced levels of antimicrobial proteins/peptides.
    1. Neuroscience

    Neurexins control the strength and precise timing of glycinergic inhibition in the auditory brainstem

    He-Hai Jiang, Ruoxuan Xu ... Fujun Luo
    Neurexins are essential for shaping the functional properties of glycinergic synapse in the auditory brainstem, further attesting their universal role as critical presynaptic organizers in all major fast chemical synapses.
    1. Neuroscience

    Principal cells of the brainstem’s interaural sound level detector are temporal differentiators rather than integrators

    Tom P Franken, Philip X Joris, Philip H Smith
    Principal neurons of the brainstem nucleus comparing sound level at the two ears do not have the slow response properties previously attributed to them, but are instead specialized for fast weighing of excitation and inhibition.
    1. Plant Biology

    Adenylnucleotide-mediated binding of the PII-like protein SbtB contributes to controlling activity of the cyanobacterial bicarbonate transporter SbtA

    Britta Förster, Bratati Mukherjee ... G. Dean Price
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Medicine

    Identification of Novel Syncytiotrophoblast Membrane Extracellular Vesicles Derived Protein Biomarkers in Early-onset Preeclampsia: A Cross-Sectional Study

    Toluwalase Awoyemi, Shuhan Jiang ... Manu Vatish
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology

    The Cl--channel TMEM16A is involved in the generation of cochlear Ca2+ waves and promotes the refinement of auditory brainstem networks in mice

    Alena Maul, Antje Kathrin Huebner ... Christian A Hübner
    Ano1 deletion disrupts Ca2+ waves within Kölliker’s organ, reduces burst-firing activity and frequency selectivity of auditory brainstem neurons in the medial nucleus of the trapezoid body, and impairs the functional refinement of its projections to the lateral superior olive.
    1. Microbiology and Infectious Disease

    Infectious polymorphic toxins delivered by outer membrane exchange discriminate kin in myxobacteria

    Christopher N Vassallo, Pengbo Cao ... Daniel Wall
    Serial cell-to-cell transfer of lipoprotein toxins by outer membrane exchange provides a potent platform for kin discrimination in Myxococcus xanthus.

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