553 results found
    1. Developmental Biology

    A-to-I RNA editing of CYP18A1 mediates transgenerational wing dimorphism in aphids

    Bin Zhu, Rui Wei ... Pei Liang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages

    Ainhoa Arbués, Sarah Schmidiger ... Damien Portevin
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Microbiology and Infectious Disease
    2. Epidemiology and Global Health

    Timely vaccine strain selection and genomic surveillance improves evolutionary forecast accuracy of seasonal influenza A/H3N2

    John Huddleston, Trevor Bedford
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer’s Disease

    Lena Kallweit, Eric D Hamlett ... Scott Horowitz
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Methylation Clocks Do Not Predict Age or Alzheimer’s Disease Risk Across Genetically Admixed Individuals

    Sebastián Cruz-González, Esther Gu ... John A Capra
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete

  6. Global South Committee for Open Science: Welcoming new members

    Three new members from the Caribbean, Indian subcontinent and Latin America join the committee to drive more inclusive, equitable and diverse scientific communication.
    1. Ecology

    Birds migrate longitudinally in response to the resultant Asian monsoons of the Qinghai-Tibet Plateau uplift

    Wenyuan Zhang, Zhongru Gu ... Xiangjiang Zhan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    Determining the effects of paternal obesity on sperm chromatin at histone H3 lysine 4 tri-methylation in relation to the placental transcriptome and cellular composition

    Anne-Sophie Pepin, Patrycja A Jazwiec ... Sarah Kimmins
    Epigenomic and transcriptomic analysis reveals that paternal obesity influences sperm histone H3 lysine 4 tri-methylation enrichment and placenta gene expression, which in turn negatively impact its development and function in a manner that may contribute to metabolic disease in offspring.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Yerba mate (Ilex paraguariensis) genome provides new insights into convergent evolution of caffeine biosynthesis

    Federico A Vignale, Andrea Hernandez Garcia ... Adrian G Turjanski
    DNA sequencing of the yerba mate (Ilex paraguariensis) genome reveals convergent genomic changes, biochemical pathways, mutations, and substrate-binding orientations responsible for caffeine biosynthesis when compared to coffee and tea plants.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Benchmarking and Optimization of Methods for the Detection of Identity-By-Descent in High-Recombining Plasmodium falciparum Genomes

    Bing Guo, Shannon Takala-Harrison, Timothy D O’Connor
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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