195 results found
    1. Genetics and Genomics
    2. Evolutionary Biology

    Admixture into and within sub-Saharan Africa

    George BJ Busby et al.
    Gene flow analysis reveals that the genomes of most sub-Saharan populations are the result of recent historical admixture events.
    1. Epidemiology and Global Health

    A century of trends in adult human height

    NCD Risk Factor Collaboration (NCD-RisC)
    Height in early adulthood is an indicator that integrates across different dimensions of sustainable human development with links to health and longevity, nutrition, education and economic productivity.
    1. Microbiology and Infectious Disease

    Unravelling the history of hepatitis B virus genotypes A and D infection using a full-genome phylogenetic and phylogeographic approach

    Evangelia-Georgia Kostaki et al.
    Considerable differences are observed in the global dissemination patterns of HBV-D and HBV-A, the genotypes of which have putative origins in North Africa/Middle East (HBV-D) and the Middle East/Central Asia (HBV-A).
    1. Microbiology and Infectious Disease

    Transgenic shRNA pigs reduce susceptibility to foot and mouth disease virus infection

    Shengwei Hu et al.
    A transgenic small hairpin RNA can provide a viable tool for enhancing resistance to viral infection in livestock and improve animal well-being.
    1. Epidemiology and Global Health
    2. Medicine

    A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean

    Rodrigo M Carrillo-Larco et al.
    In Latin America and the Caribbean the most common dyslipidaemia seems to be low HDL-cholesterol, and there has been little change in time for both mean levels and prevalence estimates.
    1. Microbiology and Infectious Disease

    Programmed knockout mutation of liver fluke granulin attenuates virulence of infection-induced hepatobiliary morbidity

    Patpicha Arunsan et al.
    Gene knockout of liver fluke granulin by CRISPR/Cas9 attenuates the virulence of infection with a carcinogenic liver fluke.
    1. Ecology
    2. Epidemiology and Global Health

    The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus

    Moritz UG Kraemer et al.
    The limits to the global distribution of the mosquitoes that transmit dengue and chikungunya have been predicted using a species distribution modelling approach.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

    Luana C Mathieu et al.
    The de novo selection of a mutation responsible for Plasmodium falciparum in vitro artemisinin resistance is confirmed in Guyana, making artemisinin combination therapies vulnerable to complete resistance in this region.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    A complete toolset for the study of Ustilago bromivora and Brachypodium sp. as a fungal-temperate grass pathosystem

    Franziska Rabe et al.
    The establishment of Ustilago bromivora and Brachypodium as a biotrophic model system provides the foundation for studying new aspects of plant-pathogen interactions and for answering questions about fungal sex and speciation.
    1. Epidemiology and Global Health

    Estimating the burden of α-thalassaemia in Thailand using a comprehensive prevalence database for Southeast Asia

    Carinna Hockham et al.
    The incorporation of as yet underused local epidemiological data on α-thalassaemia in Southeast Asia within a geostatistical model suggests that the burden of severe α-thalassaemia forms may have been underestimated.

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