166 results found
    1. Neuroscience

    Rotating waves during human sleep spindles organize global patterns of activity that repeat precisely through the night

    Lyle Muller et al.
    A phase-based analysis reveals wave-like spatiotemporal organization of the human sleep spindle, a brain oscillation critical to sleep-dependent memory consolidation, and elucidates its role in coordinating activity of neural networks distributed across the cortex.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Autocatalytic microtubule nucleation determines the size and mass of Xenopus laevis egg extract spindles

    Franziska Decker et al.
    Quantitative microscopy and theory show that the size of Xenopus laevis egg extract spindles is controlled by a spatially-regulated autocatalytic growth mechanism driven by microtubule-stimulated microtubule nucleation.
    1. Physics of Living Systems
    2. Cell Biology

    27 T ultra-high static magnetic field changes orientation and morphology of mitotic spindles in human cells

    Lei Zhang et al.
    An ultra-high static magnetic field changes mitotic spindle orientation in cells by exerting magnetic torques on both microtubules and chromosomes.
    1. Neuroscience

    Thalamic reticular control of local sleep in mouse sensory cortex

    Laura MJ Fernandez et al.
    Local cortical sleep features arise subcortically due to heterogeneous burst discharge in neurons of a sleep rhythm pacemaker previously thought to act uniformly.
    1. Neuroscience

    Cellular and neurochemical basis of sleep stages in the thalamocortical network

    Giri P Krishnan et al.
    A computational model of the thalamocortical network explains sleep stages by the coordinated variations in the level of neuromodulators and predicts differences of sleep pattern in human, cat and mouse recordings.
    1. Neuroscience

    A nap to recap or how reward regulates hippocampal-prefrontal memory networks during daytime sleep in humans

    Kinga Igloi et al.
    Sleep plays a critical role in the selectivity of memory by promoting the retention of important memories at the expense of less relevant ones.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Natural variation in stochastic photoreceptor specification and color preference in Drosophila

    Caitlin Anderson et al.
    Binding site affinity and transcription factor levels are finely tuned in nature to regulate stochastic expression, setting the ratio of alternative photoreceptor fates and determining color preference.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    The asymmetry of female meiosis reduces the frequency of inheritance of unpaired chromosomes

    Daniel B Cortes et al.
    Female meiotic spindles correct trisomy by expelling extra chromosomes into the first polar body.

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