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AFF4 increases the combined selectivity of HIV Tat and TAR for super elongation complexes 330-fold over P-TEFb alone.

The miR-106a-5p links STAT3 with TP73 to activate Pol III-dependent transcription and cancer cell proliferative activity.

STAG proteins function independently of core cohesin at R-loops to facilitate cohesin loading.

The analysis of injury-reactivated tectal radial glia in zebrafish reveals a stochastic cell-cycle entry and cell-state-dependent regulation of the balance between neurogenesis and gliogenesis.

There is a disparity in temporal and spatial relationships between resting-state electrophysiological and functional magnetic resonance imaging (fMRI) signals, suggesting the electrophysiological signal alone cannot fully explain the effects observed in the resting-state fMRI signal.

Single-cell and bulk expression analyses reveal that HCMV latent infection drives cells towards a weaker immune-responsive state, which is important for its expression and reactivation.

Tat uses unexpected regulatory mechanisms to reprogram target immune cells to promote viral replication and rewire pathways beneficial for HIV.

Protein nutritional requirements decrease predictively with mass throughout ontogeny across the animal kingdom.

RNA polymerase II generates numerous transcript isoforms, including transcripts initiating downstream of the START codon, that are efficiently degraded by the nonsense-mediated mRNA decay pathway.

Prefrontal causal roles in bistable perception are dynamically changing and determined by the brain state to which the whole-brain activity pattern belongs.