Multi-fiber photometry recording and circuit-based manipulation in vivo identify a long-range SuM-DG circuit linking two highly correlated subcortical regions to regulate spatial memory retrieval through SuM glutamate transmission.

In mouse brain slices, native delta glutamate receptors carry ionic current and underlie the α1-adrenergic receptor-mediated depolarization of dorsal raphe neurons that drives action potential firing in vivo.

Oligodendrocytes are actively engaged in the precise control of synaptic functions in the CNS through activity-dependent BDNF signaling.

Animal-to-animal variability in neuronal geometry may be compensated for by compact electrotonic structure.

Glutamate cotransmission from a subset of cortical GABAergic interneurons can promote network hyperexcitability.

Ca2+ influx through Cav1.4 channels is required for the structural, but not the molecular organization of the rod photoreceptor synapse.

Serotonergic cells innervating the Drosophila antennal lobe are inhibited by odors and modulate olfactory responses in conjunction with the entire serotonergic network.

The first patch-clamp recordings from single cerebellar granule cells during locomotion reveal that the entire step sequence can be predicted from both excitatory synaptic input and output spikes from a single neuron.

Dopaminergic input shapes activity of specialized amygdala inhibitory cell clusters by ionotropic and metabotropic mechanisms that may enable their selection during distinct fear-related behavioral states.

Inspiratory rhythmogenesis is mediated by an emergent mechanism independent of bursts associated with motor output and is modulated by opioids, pointing to strategies for ameliorating opioid-induced respiratory depression.