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    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Discovery of a metabolic alternative to the classical mevalonate pathway

    Nikki Dellas, Suzanne T Thomas ... Joseph P Noel
    A combination of phylogenetic and biochemical analyses suggest that some unexpected variations in the synthesis of isoprenoids may be widespread across all three domains of life.
    1. Structural Biology and Molecular Biophysics

    Interaction hierarchy among Cdv proteins drives recruitment to membrane necks

    Nicola De Franceschi, Alberto Blanch-Jover, Cees Dekker
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    aCPSF1 cooperates with terminator U-tract to dictate archaeal transcription termination efficacy

    Jie Li, Lei Yue ... Xiuzhu Dong
    Term-seq, genetic and biochemical experiments reveal that the trans-action factor aCPSF1 and the terminator U-tract cis-element work in a noteworthy two-in-one termination mode in archaea, and may represent an archetypal mode of the eukaryotic RNA polymerase II termination machinery.
    1. Cell Biology
    2. Evolutionary Biology

    Flagellar energy costs across the tree of life

    Paul E Schavemaker, Michael Lynch
    Prokaryotic and eukaryotic flagella follow a common trend in swimming cost-effectiveness, but eukaryotic flagella are too large for cells with prokaryote volumes, yielding insight into flagellar dissimilarity between taxa.
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