16 results found
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Switching of metabolic programs in response to light availability is an essential function of the cyanobacterial circadian output pathway

    Anna M Puszynska, Erin K O'Shea
    The circadian clock of Synechococcus elongatus PCC7942 schedules the activity of the transcription factor RpaA, which controls key events in carbon metabolism that contribute to cell fitness in conditions mimicking the natural environment.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Carboxysomes: How bacteria arrange their organelles

    Emilia Mauriello
    The structures responsible for photosynthesis in bacteria use the nucleoid and two unique proteins as a scaffold to position themselves.
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    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Protein gradients on the nucleoid position the carbon-fixing organelles of cyanobacteria

    Joshua S MacCready et al.
    Carboxysomes, the carbon-fixation machinery of cyanobacteria, are equidistantly-positioned by dynamic gradients of the protein McdA on the nucleoid that emerge through interaction with a previously unidentified carboxysome factor, McdB.
    1. Ecology
    2. Evolutionary Biology

    Emergence of trait variability through the lens of nitrogen assimilation in Prochlorococcus

    Paul M Berube et al.
    In the context of an organism's ecology, physiology, and macroevolutionary history, inheritance and gene loss can yield emergent patterns of trait variability that give the appearance of gene acquisition.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity

    Welkin H Pope et al.
    A continuum of genome relationships is discovered through comparative genomics of 627 sequenced mycobacteriophages isolated and characterized in an integrated research/education initiative.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Crystal structures of virus-like photosystem I complexes from the mesophilic cyanobacterium Synechocystis PCC 6803

    Yuval Mazor et al.
    The structure of the photosystem I (PSI) complex from Synechocystis is determined, and reaction center subunits engineered to resemble a viral PSI are found to promote promiscuous electron acceptor properties.
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Adaptation of hydroxymethylbutenyl diphosphate reductase enables volatile isoprenoid production

    Mareike Bongers et al.
    Differences in HDR product preference present a novel mechanism in plants to control substrate availability for short- and long-chain isoprenoids.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Quantitative insights into the cyanobacterial cell economy

    Tomáš Zavřel et al.
    Phototrophic growth laws are elucidated by combining computational modeling and experiments for quantitative evaluation of cellular physiology, morphology and proteome allocation across a wide range of light conditions.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria

    Joseph Robert Piechura et al.
    Cyanobacteria cope with both predictable day/night changes and natural fluctuations in light during the day by adjusting the expression dynamics of circadian-clock-controlled genes via a network of transcriptional regulators.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    The cyanobacterial circadian clock follows midday in vivo and in vitro

    Eugene Leypunskiy et al.
    The cyanobacterial core clock tracks midday regardless of day length, which can be understood in terms of a model for how the environment alters the clock limit cycle.

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