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Cardiac fibroblast reduction is well-tolerated and demonstrates beneficial outcomes after heart injury.

T-regulatory type 1 cells inherit a broad repertoire of epigenetic marks from T-follicular helper T-cells, offering new insights into the developmental biology of this subset.

Metabolomics analysis identified potential neuroactive metabolites, issued from food and microbial fermentation, that are linked to symptoms of depression, anxiety and alcohol craving.

A high-resolution picture of genetic complexity and network perturbations underlying cardiac inter-atrial septal dysmorphology associated with patent foramen ovale, a common human congenital anomaly, using quantitative trait locus mapping, genome sequencing, and transcriptomics in a mouse model.

The phagocytic receptor CED-1 is kept at the appropriate level by E3 ligase trim-21-mediated ubiquitination-proteasomal degradation for apoptotic cell clearance, which is independent of retromer-dependent recycling and lysosomal degradation.

A high-throughput microscopy screen for drugs that modulate SARS-CoV-2 spike-mediated membrane fusion identifies an essential role for cholesterol in both virus entry and syncytia formation.

Altered lymphocyte dynamics after hematopoietic stem cell transplantation cannot solely be explained by low lymphocyte numbers.

Depending upon the parameters used, neuromuscular stimulation can have beneficial or deleterious impacts on muscle structure and function in an animal model of Duchenne muscular dystrophy.

Cst7, a gene coding for protein cystatin F, is expressed by microglia in neurodegenerative disease models and mediates sex-dependent effects on microglial endolysosomal function and disease pathology.