1,502 results found
    1. Cell Biology
    2. Immunology and Inflammation

    Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility

    Akira Takeda et al.
    A lipid mediator lysophosphatidic acid (LPA) derived from fibroblastic reticular cells regulates T-cell movement through the densely packed reticular network in lymph nodes in a manner dependent on the LPA receptor LPA2-ROCK-myosin II.
    1. Cell Biology
    2. Immunology and Inflammation

    Intermittent Ca2+ signals mediated by Orai1 regulate basal T cell motility

    Tobias X Dong et al.
    Orai1 channels activate intermittently in motile T cells, generating calcium transients, detected by a novel genetically encoded indicator and inducing pauses that favor antigen scanning.
    1. Cell Biology
    2. Immunology and Inflammation

    T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse

    Tobias X Dong et al.
    Salsa6f is a novel, ratiometric genetically encoded Ca2+ indicator that combines the power of ratiometric chemical Ca2+ indicators with the ability, when expressed transgenically, to image cellular Ca2+ signals amid complex tissue environments in vivo.
    1. Epidemiology and Global Health

    Science Forum: Unit of analysis issues in laboratory-based research

    Nick R Parsons et al.
    A simulation study is used to demonstrate how mistakes in identifying the experimental unit and the unit of analysis can lead to incorrect analyses and inappropriate inferences when reporting research studies.
    1. Human Biology and Medicine
    2. Neuroscience

    Point of View: Predictive regulation and human design

    Peter Sterling
    Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?
    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev et al.
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.
    1. Cell Biology
    2. Ecology

    The Natural History of Model Organisms: From molecular manipulation of domesticated Chlamydomonas reinhardtii to survival in nature

    Severin Sasso et al.
    Dubbed the 'green yeast', the model alga C. reinhardtii has profoundly advanced many areas of biology, but much remains to be learnt about its life in the wild.
  1. Point of View: How should novelty be valued in science?

    Barak A Cohen
    An over-emphasis on novelty is having detrimental effects on science.
    1. Physics of Living Systems

    Point of View: Are theoretical results ‘Results’?

    Raymond E Goldstein
    There should be a prominent place for theory within biology papers, both as Results in papers that combine experiment and theory, and as Results in theory papers.

Refine your results by:

Type
Research categories