In addition to the well-established involvement of descending neural tracts, the left-right side-specific endocrine mechanism may contribute to signaling from injured brain to spinal motor circuits.

Analysis of 3D paw kinematics and whole-body coordination in freely walking mice isolates specific features of gait ataxia and supports the hypothesis that the cerebellum provides an internal forward model for motor control.

In vivo modulation of the prostaglandin, interferon, or granulocyte colony-stimulating factor pathway induces rapid and specific transcriptional changes in hematopoietic stem cells with significant heterogeneity in the cellular response.

In the Drosophila central brain, synaptic connectivity extracts visual-spatial information from the axons of looming sensitive LC6 neurons that terminate in a glomerulus with minimal retinotopy.

A mutant impaired for ribosome recycling exhibits translational reprogramming wherein strong mRNAs outcompete weak mRNAs, also observed when preinitiation complexes are diminished by eIF2α phosphorylation or 40S ribosomal subunit depletion.

SIMR-1 acts downstream of the piRNA pathway to promote siRNA amplification by the Mutator complex and localizes to perinuclear foci distinct from Mutator foci, P granules and Z granules.

To maintain genomic integrity during oocyte development, the tumor suppressor BRCA1/BRC-1 and the SMC-5/6 complex both repress intersister crossover recombination events while BRCA1/BRC-1 also specifically inhibits error prone repair of DNA breaks during meiotic prophase I.

Somatic aging and germline RNAi pathways promote inheritance of ancestral starvation memory through reallocation of fat storage in Caenorhabditis elegans.

Simulations reveal where phosphoinositide lipids bind to voltage-gated sodium channels and how they reduce channel activity.

The gene-regulatory enhancers h56D and S5E2 restrict transgene expression to GABAergic and parvalbumin-positive interneurons, respectively, across marmoset cortical layers, thus representing a promising tool for circuit dissection in non-human primates.