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AXL enables the priming of the antiviral adaptive immune response by limiting the production of type I interferons in dendritic cells.

A multiplexed retrograde virus tracing method captures single-neuron projectome and transcriptome simultaneously.

A screen of visual-experience induced changes in newly-synthesized proteins in Xenopus optic tectum identifies unexpected candidate plasticity proteins.

Chromosomal instability through spindle assembly checkpoint alleviation facilitates malignant transformation of hepatocytes and T-cells in vivo, resulting in cancers with recurrent karyotypes.

The development of Natural Killer T Cells is controlled by Histone Deacetylase 7, a function that combined with its known role in thymic negative selection provides a potential mechanism explaining its association with tissue-specific autoimmunity in humans.

Feathered feet of pigeons and chickens result from a partial molecular and morphological transformation of legs to a wing-like identity.

A chemical biology approach has identified the kinase DYRK1A as a new regulator of the inflammatory response.

Pre-existing enhancers interpret T cell signaling strength in an analogue manner to direct quantitative changes in gene expression within the context of an overall digital response.

While tau and aging have highly overlapping differential gene expression signatures, they diverge in the affected cell types, with aging having a wide-ranging impact and tau-triggered changes instead polarized to excitatory neurons and glia.

Different types of epigenetic DNA modifications affect the likelihood of cytosine mutations in cancer.