305 results found
    1. Chromosomes and Gene Expression

    A gene-specific T2A-GAL4 library for Drosophila

    Pei-Tseng Lee et al.
    A library of a thousand gene-specific intronic GAL4 insertions was generated, which caused a severe loss of function, permitted the assessing of gene expression, allowed the rescue of mutated gene with UAS-cDNA constructs, and provided a tool for the reversion of mutant phenotypes in specific cells or tissues.
    1. Genetics and Genomics

    An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila

    David Li-Kroeger et al.
    New technology for manipulating genes in Drosophila facilitates gene tagging and precise modification of virtually any gene.
    1. Neuroscience

    A kinase-dependent feedforward loop affects CREBB stability and long term memory formation

    Pei-Tseng Lee et al.
    Through an image and behavioral screen based on MiMIC technology, we identified a novel kinase, CG11221 renamed Meng-Po (MP), and showed that flies that lack MP in mushroom bodies can learn but cannot remember as MP is required for the protein stability of CREBB.
    1. Developmental Biology
    2. Evolutionary Biology

    Developmental variability channels mouse molar evolution

    Luke Hayden et al.
    The nature and extent of developmental variation seen between mouse strains and genetically identical individuals explain why the first upper molar evolves along preferred path in murine rodents.
    1. Neuroscience

    In vivo assessment of the neural substrate linked with vocal imitation accuracy

    Julie Hamaide et al.
    Song learning accuracy can be predicted and traced in the structural properties of the brains of juvenile male zebra finches already at 20 days post-hatching.
    1. Genetics and Genomics
    2. Neuroscience

    A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord

    Aaron M Allen et al.
    A single-cell atlas of the adult fly VNC charts the types and properties of cells for future studies of brain development and function.
    1. Neuroscience

    Cre-assisted fine-mapping of neural circuits using orthogonal split inteins

    Haojiang Luan et al.
    A genetic method allows neurons to be individually identified and characterized by combining information about both their developmental origins and their mature patterns of gene expression.
    1. Developmental Biology

    Antagonistic regulation by insulin-like peptide and activin ensures the elaboration of appropriate dendritic field sizes of amacrine neurons

    Jiangnan Luo et al.
    Afferent-derived factors control the elaboration of appropriate and robust sizes of dendritic arbors by dynamically modulating dendritic growth parameters.
    1. Biochemistry and Chemical Biology

    The GTPase Nog1 co-ordinates the assembly, maturation and quality control of distant ribosomal functional centers

    Purnima Klingauf-Nerurkar et al.
    The GTPase Nog1 orchestrates stalk assembly, peptidyl transferase centre maturation and polypeptide exit tunnel quality control.
    1. Neuroscience

    Homeostatic plasticity fails at the intersection of autism-gene mutations and a novel class of common genetic modifiers

    Özgür Genç et al.
    Forward genetic screens define a novel genetic landscape by which diverse, unrelated autism risk genes may converge to commonly affect the robustness of synaptic transmission.

Refine your results by:

Type
Research categories