Connectomic analysis identifies the complex circuits of a visual motion-sensing neuron that qualify them to generate direction-selective motion sensing signals using both Hassenstein-Reichardt and Barlow-Levick models.

Biochemical and genetic experiments show that Ebf and Lhx2 cooperate to specify olfactory receptor enhancers, which cooperate to drive olfactory receptor expression.

Certain types of 3D chromatin loops are easy to predict from existing or easily obtainable 2D information, which benefits gene expression studies in tissues/cells/organisms without extensive pre-existing 3D information.

An image-based multiplex autophagosome RNAi screen targeting all Rab GTPases as well as their GAPs and GEFs identifies the Rab GEF SMCR8 as multifaceted autophagy modulator, which regulates kinase activity and gene expression of ULK1.

Full length RTN3 homodimerization mediates ER tubules fragmentation and their subsequent delivery to lysosome.

An integrative genome-wide approach supports a direct and collaborative role of ETS and AP-1 transcription factors in maintaining endothelial cell-specific and anti-inflammatory gene expression programs.

Small regulatory RNAs are able to modulate mRNA degradation rates by controlling access to the 5' end of mRNAs in bacteria.

Promoter interactome maps in human embryonic stem cells (ESCs) and ESC-derived early neuroectodermal progenitors link distal enhancers to putative target genes, reveal lineage-specific cis-regulatory architecture and shed light on the logic of gene regulation by multiple enhancers.

The METHYL-CpG-BINDING DOMAIN 7 (MBD7) complex promotes the activation (rather than repression) of transgenes that undergo DNA methylation and it does so without significantly altering their methylation status, placing this complex downstream of DNA methylation.