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    1. Neuroscience

    DYT1 dystonia increases risk taking in humans

    David Arkadir et al.
    Patients with DYT1 dystonia show aberrant risk-aversion in a simple decision-making task, in accordance with predictions of a reinforcement learning model of corticostriatal trial-and-error learning.
    1. Neuroscience

    Instructed knowledge shapes feedback-driven aversive learning in striatum and orbitofrontal cortex, but not the amygdala

    Lauren Y Atlas et al.
    While the striatum and orbitofrontal cortex learn about threats through verbal warnings, the amygdala learns only from direct experience, suggesting that the amygdala forms part of a specialized threat detection system.
    1. Computational and Systems Biology
    2. Neuroscience

    Dopamine role in learning and action inference

    Rafal Bogacz
    A mathematical model describes the function of dopaminergic neurons in both learning and action planning.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets

    Palur V Raghuvamsi et al.
    SARS-CoV-2 spike protein binding to receptor angiotensin-converting enzyme 2 allosterically enhances furin proteolysis at distal S1/S2 cleavage sites.
    1. Genetics and Genomics
    2. Neuroscience

    A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons

    Benjamin W Okaty et al.
    Dorsal raphe Pet1 neurons are molecularly heterogeneous, comprising as many as fourteen distinct subtypes that show biased cell body distributions across dorsal raphe subdomains.
    1. Cell Biology

    Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

    Leilei Zhong et al.
    A newly identified adipose lineage cell population, MALP, regulates marrow vasculature and osteogenesis in bone.
    1. Evolutionary Biology

    Retinal oxygen supply shaped the functional evolution of the vertebrate eye

    Christian Damsgaard et al.
    Multiple respiratory and vascular mechanisms have recurrently evolved across the vertebrates to alleviate the oxygen diffusion limitations inherent to the morphology of the retina.
    1. Ecology
    2. Evolutionary Biology

    Signal categorization by foraging animals depends on ecological diversity

    David William Kikuchi et al.
    In richer, more even communities, foragers form broad categories among their food resources that can select for convergence among signals, including mimetic resemblances.
    1. Evolutionary Biology

    Expansion of the fatty acyl reductase gene family shaped pheromone communication in Hymenoptera

    Michal Tupec et al.
    A fatty acyl reductase gene family expansion in the Hymenoptera crown group led to recruitment of novel pheromone-biosynthetic enzymes and is linked to evolution of pheromone marking behavior.