532 results found
    1. Microbiology and Infectious Disease

    Bacteria: How Legionella defend their turf

    Elisa D Hughes, Michele S Swanson
    Communities of bacteria that cause Legionnaire’s disease repel other bacteria by secreting an acid called HGA.
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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    DNA-PK is a DNA sensor for IRF-3-dependent innate immunity

    Brian J Ferguson et al.
    Experiments in mice have shown than an enzyme that repairs broken DNA inside the nucleus also has a central role in the innate immune system because it is able to detect foreign DNA outside the nucleus.
    1. Cell Biology
    2. Plant Biology

    TIR1/AFB-Aux/IAA auxin perception mediates rapid cell wall acidification and growth of Arabidopsis hypocotyls

    Matyáš Fendrych et al.
    The nuclear pathway for auxin perception is responsible for the rapid auxin-induced cell wall acidification and growth of aerial organs of plants.
    1. Structural Biology and Molecular Biophysics

    Myosin motors fragment and compact membrane-bound actin filaments

    Sven K Vogel et al.
    A combination of single-molecule imaging and an in vitro model of the cell cortex has allowed the interactions between actin filaments and filaments made of myosin II to be studied in detail.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Cellular encoding of Cy dyes for single-molecule imaging

    Lilia Leisle et al.
    Cyanine fluorophores are encoded as non-canonical amino acids to produce functional proteins in cell-free translation systems and live cells for single-molecule imaging.
    1. Immunology and Inflammation

    Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses

    Shiho Chiba et al.
    An immune system pattern recognition receptor potentiates anti-tumor innate immune responses, offering new insight into anti-tumor activity of the innate immune system.
    1. Physics of Living Systems
    2. Cell Biology

    Side-binding proteins modulate actin filament dynamics

    Alvaro H Crevenna et al.
    The kinetics of actin polymerization are strongly influenced by the binding of proteins to the lateral filament surface.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation

    Benjamin A Smith et al.
    New insights into the mechanism responsible for the nucleation of branches on networks of actin filaments shed light on a process that is essential for eukaryotic cell motility and endocytosis.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements

    Julene Madariaga-Marcos et al.
    A single-molecule biophysical approach reveals that the C-terminal domain of ParB blocks ParB network formation by heterodimerization with the full-length protein, which remains bound to the DNA.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    The size of the EB cap determines instantaneous microtubule stability

    Christian Duellberg et al.
    The EB binding region defines the length of the protective cap that stabilizes growing microtubules.

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