Drosophila use distinct sensory mechanisms to detect and integrate the same tactile and taste information in two decision-making tasks that serve two different purposes.

Multi-dendritic cibarium neurons in the fly pharynx sense mechanical force during swallowing by NOMPC, piezo, and Tmc, besides, these neurons interact with motor neurons to control food swallow.

Drosophila suzukii, which lays eggs on ripe fruits, differs from Drosophila melanogaster in sweet sensation, mechanosensation, and their integration.

Genetic deficits in auditory sensory transduction evoke changes in development and maturation of synapses between inner hair cells and spiral ganglion neurons, which can be partially recovered using inner ear gene therapy.

Gut-innervating sensory neurons detect large food volumes and inhibit feeding in Drosophila through the mechanically gated ion channel Piezo.

Complexes formed by calcium- and integrin-binding proteins 2 and 3 and transmembrane channel-like proteins 1 and 2 are essential for vertebrate hearing and balance and for fish lateral line function.

Other than its function in mechanotransduction, TMC1 is indispensable for action potential firing of auditory hair cells by mediating a leak conductance that alters tonotopically along the cochlea coil.

Single-nucleus sequencing, anatomy, and physiology reveal heterogeneity among olivocochlear neurons (a group of cells that provide feedback to the inner ear), identify a neuropeptide-enriched subtype, and show that neuropeptide expression changes during postnatal development and after sound exposure.

The remarkable lifelong stability of mechanotransducing stereocilia of the inner ear hair cells depends on the activity of the transduction ion channels located at the tips of these mechanosensory projections.

A fly larval mechanical nociceptor develops dedicated neuronal mechanisms to support its sensory preference in detecting localized poking forces, and this sensory feature well supports the physiological function of the nociceptor in sensing the physical attack of its natural enemy.