Browse the search results

LXA₄ in lymph nodes is an important resident homeostatic regulator that controls effector T cell functions and egress in the development of adaptive immune responses.

Hepatocyte RIPK1 plays an important role in liver physiology, preventing liver injury and inflammation during metabolic stresses like acute fasting.

Age-related tendon degeneration is initiated by loss of tenocytes associated with synthesis of high-turnover rate proteoglycans and glycoproteins.

Changes in the interactome of the Rel family of transcription factors control adaptation to the environmental stress of hyperosmolarity and determine cell fate.

Deep and comprehensive proteomic resource of human intervertebral disc at high spatial resolution with a methodological flow reveals new insights in disc homeostasis and degeneration.

Dysfunction and overexpression of ENaC-mediated sodium influx exacerbates activation of NLRP3-inflammasome mediated inflammation in cells with CF-associated mutations and is modulated by inhibition of these amiloride-sensitive sodium (Na⁺) channels.

Full spectrum flow cytometry reveals a high degree of placental mesenchymal cell heterogeneity, which is lost with culture, highlighting the importance of detailed ex vivo phenotyping to optimise the use of these cells in downstream applications.

Maternal obesity and high-fat diet present metabolic, signaling, and epigenetic impediments to pathogen recognition in fetal innate immune cells that result in a state of immune paralysis during gestation and at birth.

The endosymbiosis between an alga and the spotted salamander shows several parallels to invertebrate-algal symbioses as well as to pathogen associations in vertebrate animals.

A live imaging and computational approach reveals feedback loops involving F-actin dynamics that regulate the NF-κB transcription factor RELA.