An interaction between two proteins enables the spindle—the structure that segregates chromosome pairs during mitosis—to change size as cells divide.

Sensory neurons in the olfactory system develop from two different regions of the ectoderm, the olfactory placode and the cranial neural crest, whereas sensory neurons within the eye and ear develop from just one region.

Computer simulations reveal that viral nucleic acids have an ideal structure for being packaged into outer protein shells called capsids.

A cysteine-rich domain within the Smoothened receptor may represent a novel therapeutic target for cancers caused by abnormal functioning of the Hedgehog signaling pathway.

Cells from the human pancreatic duct can be grown in culture and triggered to become insulin-producing cells, which could potentially be transplanted into patients with diabetes.

The first in vitro analysis of full-length human Kif15 provides insight into how hKif15 and its inhibitory binding partner hTpx2 modulate mitotic spindle architecture.

A chemical method has been developed for studying single organ regeneration and fate specification of stem cells in an adult organism.

The repair of spontaneous DNA damage can introduce mutators that lead to further genetic changes, which could underlie evolutionary change, disease and aging.

A missing link between the AP complexes and COPI sheds light on the evolution of vesicle coat proteins and trafficking pathways in the earliest eukaryotes.