3,473 results found
    1. Plant Biology
    2. Evolutionary Biology

    Herbivory-induced volatiles function as defenses increasing fitness of the native plant Nicotiana attenuata in nature

    Meredith C Schuman, Kathleen Barthel, Ian T Baldwin
    A 2-year field study has demonstrated that volatile compounds produced by plants when they are attacked by herbivores act as defenses by attracting predators to the herbivores and increasing the reproduction of the plants.
    1. Cell Biology

    The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis

    Philipp Kimmig, Marcy Diaz ... Peter Walter
    A unique form of regulation has been observed in the unfolded protein response of S. pombe, along with a novel mechanism of post-transcriptional mRNA processing.
    1. Cell Biology
    2. Immunology and Inflammation

    Sequence specific detection of bacterial 23S ribosomal RNA by TLR13

    Xiao-Dong Li, Zhijian J Chen
    A pattern recognition receptor called toll-like receptor 13 detects pathogens in a manner that is different to that seen in other pathogen sensors.
    1. Biochemistry and Chemical Biology

    Membrane immersion allows rhomboid proteases to achieve specificity by reading transmembrane segment dynamics

    Syed M Moin, Sinisa Urban
    Intramembrane proteases identify target proteins in a different way from other proteases.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

    Jiajie Diao, Patricia Grob ... Axel T Brunger
    A combination of advanced optical imaging and cryogenic electron microscopy has been used to explore membrane fusion in a synthetic system and provide new insights into neurotransmitter release.
    1. Structural Biology and Molecular Biophysics

    Modelling dynamics in protein crystal structures by ensemble refinement

    B Tom Burnley, Pavel V Afonine ... Piet Gros
    A combination of molecular dynamics simulations and X-ray diffraction data has been used to construct more realistic models of proteins and to provide new insights into their interactions with other proteins and biomolecules.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    DNA-PK is a DNA sensor for IRF-3-dependent innate immunity

    Brian J Ferguson, Daniel S Mansur ... Geoffrey L Smith
    Experiments in mice have shown than an enzyme that repairs broken DNA inside the nucleus also has a central role in the innate immune system because it is able to detect foreign DNA outside the nucleus.
    1. Structural Biology and Molecular Biophysics

    rsEGFP2 enables fast RESOLFT nanoscopy of living cells

    Tim Grotjohann, Ilaria Testa ... Stefan Jakobs
    The discovery of a fluorescent protein that can be rapidly switched between long-lived ‘on’ and ‘off’ states will lead to a new generation of super-resolution imaging experiments on living cells.

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