2,397 results found
    1. Genetics and Genomics

    Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes

    Shuai Zhang, Ruixue Wang ... Lin Sun
    Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
    1. Cell Biology

    AXONAL distribution of mitochondria maintains neuronal autophagy during aging via eIF2β

    Kanako Shinno, Yuri Miura ... Kanae Ando
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Sensory experience controls dendritic structure and behavior by distinct pathways involving degenerins

    Sharon Inberg, Yael Iosilevskii ... Benjamin Podbilewicz
    Mechanosensory isolation of C. elegans nematodes independently induces homeostatic structural changes in the dendritic tree and differential response to mechanical stimulation, both these structural and behavioral outcomes are mediated by degenerins and do not affect presynaptic calcium dynamics.
    1. Medicine

    Evaluating Study Design Rigor in Preclinical Cardiovascular Research: A Replication Study

    Isaiah C Jimenez, Gabrielle C Montenegro ... Adrienne Mueller
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Artesunate, EDTA and colistin work synergistically against MCR-negative and -positive colistin-resistant Salmonella

    Yajun Zhai, Peiyi Liu ... Yajun Zhai
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Medicine

    Efficacy and safety of neoadjuvant stereotactic body radiation therapy plus dalpiciclib and exemestane for hormone receptor-positive, HER2-negative breast cancer: A prospective pilot study

    Yu Zhang, Shuo Cao ... Caigang Liu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Integration of parallel pathways for flight control in a hawkmoth reflects prevalence and relevance of natural visual cues

    Ronja Bigge, Rebecca Grittner, Anna Stöckl
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response

    Long-Feng Lu, Can Zhang ... Shun Li
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    Cell crowding induces TRPV4 inhibition and its relocation to plasma membranes, implicating pro-invasive cell volume reduction mechanotransduction pathway

    Xiangning Bu, Nathanael Ashby ... Inhee Chung
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Tripartite organization of brain state dynamics underlying spoken narrative comprehension

    Lanfang Liu, Jiahao Jiang ... Guosheng Ding
    Hidden Markov Modeling to fMRI data reveals how language comprehension arises from the dynamic interplay of large-scale brain networks.
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