35 results found
    1. Neuroscience

    Neural substrates of cold nociception in Drosophila larva

    Atit A. Patel, Albert Cardona, Daniel N. Cox
    Not revised
    Reviewed Preprint v1
    • Useful
    • Convincing
    • Incomplete
    1. Evolutionary Biology
    2. Genetics and Genomics

    Genome streamlining in a minute herbivore that manipulates its host plant

    Robert Greenhalgh, Wannes Dermauw ... Merijn R Kant
    The genome of a tiny tomato pest reveals mechanisms that underlie metazoan genome reduction.
    1. Cell Biology

    TRPγ regulates lipid metabolism through Dh44 neuroendocrine cells

    Dharmendra Kumar Nath, Subash Dhakal, Youngseok Lee
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Neuroscience

    Insights into the dynamic control of breathing revealed through cell-type-specific responses to substance P

    Nathan A Baertsch, Jan-Marino Ramirez
    The neuromodulator substance P enhances mechanisms of recurrent excitation between breaths to control breathing frequency and stability.
    1. Immunology and Inflammation

    G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs

    Yi-Hong Li, Yi-Sen Yang ... Liquan Huang
    Conditional abolishment of a G protein subunit in a subset of ectopic tuft cells engenders severer injury, slower recovery, and increased fatality following the infection of the influenza viruses.
    1. Neuroscience

    Chloride-dependent mechanisms of multimodal sensory discrimination and nociceptive sensitization in Drosophila

    Nathaniel J Himmel, Akira Sakurai ... Daniel N Cox
    Anoctamin/TMEM16 and SLC12 co-transporter genes selectively function in regulating cold nociception via excitatory chloride currents and can promote neuropathic sensitization phenotypes, including behavioral sensitization and neuronal hyperexcitability in Drosophila multimodal sensory neurons.
    1. Ecology
    2. Evolutionary Biology

    Comparative genomics explains the evolutionary success of reef-forming corals

    Debashish Bhattacharya, Shobhit Agrawal ... Paul G Falkowski
    The analysis of 20 coral genomic datasets provides unprecedented insights into what makes reef-building corals unique, including the evolution of novel gene families involved in biomineralization, signaling and stress responses that have led to their evolutionary success throughout the Phanerozoic Eon.
    1. Neuroscience

    Drosophila TRPγ is required in neuroendocrine cells for post-ingestive food selection

    Subash Dhakal, Qiuting Ren ... Youngseok Lee
    Genetic, behavioral, and biochemical evidence reveals that the Drosophila TRPγ channel is required in neuroendocrine cells for the starvation-induced switch in preference to less palatable but more nutritive food.
    1. Cell Biology
    2. Neuroscience

    TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis

    Zhong-Jiao Jiang, Wenping Li ... Liang-Wei Gong
    Electrophysiological and live-cell imaging analyses identify a presynaptic function of Ca2+ influx via transient receptor potential melastatin 7 (TRPM7) channels.
    1. Neuroscience
    2. Computational and Systems Biology

    Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila

    Jayati Gera, Marishia Agard ... Meet Zandawala
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete

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