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CCDC146 is a structural component of the flagellum in sperm, located in the doublet microtubules of the axoneme, whose absence leads to multiple morphological anomalies of the flagellum.

CFAP52 is a candidate for genetic diagnosing male infertility with defects of sperm head-tail connection and flagella development.

Phosphorylation of the pseudokinase Ulk4 by Stk36 promotes primary ciliary tip localization of both proteins to facilitate the phosphorylation and activation of Gli in response to Sonic hedgehog.

Bi-allelic mutations in ZMYND12, encoding a novel axonemal protein interacting with TTC29 and DNAH1, cause male infertility and flagellum defects in human and Trypanosoma.

Mitochondrial functional and structural defects caused by PARL deficiency lead to arrested spermatogenesis and germ cell ferroptosis.

Nearly half of bladder cancers of solid organ transplant recipients harbor papillomaviruses or polyomaviruses, with many tumors showing evidence of clonal viral integration and viral oncogene effects on tumor gene expression patterns.

Specific glutamylation of some α-tubulin isotypes affects kinesin-1 localization and transport processes that depend on it, but their absence can speed up transport, possibly explaining why some large cells express α-tubulin isotypes that are not glutamylated.

The spatial organization of pathogenic bacteria into microcolonies can be shaped by the stiffness of the substrate that they colonize, via modifications of the bacterial motility.

Based on the proteomics results, T1 CRC LNM prediction models were built using machine learning, the functional differences and biomarkers between LNM-negative and LNM-positive patients were revealed.

Zebrafish genetics and sperm cryo-electron tomography reveal a novel function of Calaxin as a docking complex component stabilizing the outer arm dynein onto the ciliary doublet microtubule.