3,313 results found
    1. Plant Biology

    Phosphoprotein SAK1 is a regulator of acclimation to singlet oxygen in Chlamydomonas reinhardtii

    Setsuko Wakao et al.
    SAK1, a novel cytoplasmic phosphoprotein, is a key intermediate component of the retrograde signaling pathway controlling nuclear gene expression during acclimation of Chlamydomonas cells to singlet oxygen stress.
    1. Cancer Biology
    2. Cell Biology

    p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway

    Pauline Jeannot et al.
    p27Kip1 directly controls invadopodia turnover by promoting the interaction of PAK1 with Cortactin, which induces Cortactin phosphorylation, invadopodia disassembly and facilitates invasion through extracellular matrix.
    1. Cell Biology
    2. Developmental Biology

    Discovery of novel determinants of endothelial lineage using chimeric heterokaryons

    Wing Tak Wong et al.
    Bioinformatic analysis of gene expression in chimeric heterokaryons can identify novel regulators of cell lineage.
  1. Living Science: The rites of spring, Take 2

    Eve Marder
    Recruiting PhD students can be a frustrating process, but Eve Marder looks forward to welcoming the latest crop in the autumn.
    1. Stem Cells and Regenerative Medicine
    2. Microbiology and Infectious Disease

    Pathogenic shifts in endogenous microbiota impede tissue regeneration via distinct activation of TAK1/MKK/p38

    Christopher P Arnold et al.
    An innate immune system signaling pathway in planarians has a dual role: it enhances apoptosis during bacterial infection, but represses apoptosis during tissue regeneration in the absence of infection.
    1. Cell Biology

    Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1

    Jonathan Mowers et al.
    Reduced energy expenditure in obesity may result from reduced sensitivity to sympathetic activation due to inflammation-generated signals in adipose tissue.
  2. eLife Ambassadors: An invitation to take part in 2019

    The eLife Early-Career Advisory Group open applications for researchers who wish to join the second edition of the community advocacy programme.
  3. eLife references: Yes, we take any format; no, we're not rekeying

    Authors can use any reference style when they submit their work to eLife.

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