A unique form of regulation has been observed in the unfolded protein response of S. pombe, along with a novel mechanism of post-transcriptional mRNA processing.

Electron microscopy has been used to produce the first three-dimensional image of the PRC2 gene-silencing complex.

Intramembrane proteases identify target proteins in a different way from other proteases.

Genome-wide measurements on mouse liver cells show that transcription, and a particular key transcription factor, have a smaller than expected influence on the mouse circadian system.

A chromatin boundary factor that is only active during early embryo development has been discovered in Drosophila.

A DNA–protein complex can find target sequences of bases in another DNA molecule by sliding along it.

A combination of advanced optical imaging and cryogenic electron microscopy has been used to explore membrane fusion in a synthetic system and provide new insights into neurotransmitter release.

Structural and functional studies of a potassium ion channel that is opened and closed by different ligands have revealed a novel gating mechanism.

A protein that can recognize regions of DNA with a high proportion of unmethylated CpG dinucleotides, and then recruit polycomb group proteins to these CpG islands, has been identified.

Preventing premature interactions between microtubules and protein-based structures called kinetochores ensures that chromosomes are segregated by meiosis rather than mitosis in reproductive cells.