11,176 results found
    1. Ecology

    Biodiversity mediates the effects of stressors but not nutrients on litter decomposition

    Léa Beaumelle et al.
    The consequences of real-world biodiversity change for ecosystem functioning depend on the type of global change driver and can be particularly significant when human activities decrease biodiversity.
    1. Neuroscience

    Cross-species cortical alignment identifies different types of anatomical reorganization in the primate temporal lobe

    Nicole Eichert et al.
    Cross-species alignment based on cortical myelin content can dissociate cortical expansion and relocation from changes in connectivity profiles in the temporal lobe of higher primates.
    1. Biochemistry and Chemical Biology

    Evolutionary and functional insights into the mechanism underlying body-size-related adaptation of mammalian hemoglobin

    Olga Rapp, Ofer Yifrach
    Hemoglobin affinity and cooperativity reveal mechanistic insights in how the relation between physiology and evolutionary variations shape a protein's molecular property.
    1. Plant Biology

    Anisotropic growth is achieved through the additive mechanical effect of material anisotropy and elastic asymmetry

    Firas Bou Daher et al.
    Growing upwards in the young seedling is controlled by two cooperative mechanical mechanisms: cellulose orientation in inner tissues and differential elasticity in epidermal cells.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    The cyanobacterial circadian clock follows midday in vivo and in vitro

    Eugene Leypunskiy et al.
    The cyanobacterial core clock tracks midday regardless of day length, which can be understood in terms of a model for how the environment alters the clock limit cycle.
    1. Cancer Biology
    2. Cell Biology

    Club cells form lung adenocarcinomas and maintain the alveoli of adult mice

    Magda Spella et al.
    Airway cells are required for the maintenance of the adult mouse lung and for carcinogen-induced lung adenocarcinoma development, and are thus marked therapeutic targets.
    1. Microbiology and Infectious Disease
    2. Medicine

    A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults

    Nguyen TH Mai et al.
    Adjunctive aspirin may reduce new brain infarcts and deaths in the first 60 days of treatment for HIV-uninfected adults with tuberculous meningitis.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Fitness benefits in fluoroquinolone-resistant Salmonella Typhi in the absence of antimicrobial pressure

    Stephen Baker et al.
    The major evolutionary routes to drug resistance in Salmonella Typhi are associated with fitness benefits, not fitness costs, implying that prudent antimicrobial use will have no effect as a public health intervention in controlling typhoid fever.
    1. Immunology and Inflammation

    Natural Tr1-like cells do not confer long-term tolerogenic memory

    Koshika Yadava et al.
    Natural Tr1-like cells do not form a functionally stable memory response to allergens, and this instability may limit efforts to re-establish tolerance by expanding Tr1.
    1. Developmental Biology
    2. Neuroscience

    Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space

    Travis A Babola et al.
    Supporting cells in the cochlea change their shape in response to purinergic receptor activation, which influences hair cell excitability by altering potassium redistribution in the extracellular space.

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