A newly identified immunometabolic mechanism clarifies the aberrant trafficking of dendritic cells to lymph nodes in tuberculosis.

Sloths, armadillos, and anteaters evolved genetic and cellular traits that make them remarkably cancer resistant.

Zebrafish provide unique resources for the study of the tumor microenvironment.

Auxin-inducible degradation of CRISPR-tagged endogenous proteins in mice reveals cell-type-specific dependence on the mitotic chromosome condensation proteins.

High-throughput phenotypic screening followed by unbiased target identification reveals a new molecular glue HQ461 that induces CDK12-DDB1 interaction to promote degradation of Cyclin K via the ubiquitin proteasome system.

Operant drug self-administration in a mouse model of neuropathic pain reveals pain-relieving effects of a cannabinoid CB₂ receptor agonist that are mediated through CB₂ receptors of neurons and lymphocytes.

The new drug 3,6’-dithiopomalidomide mitigates key markers of neuronal death and neuroinflammation and improves acute behavioral outcome measures in traumatic brain injury, a common, debilitating disorder that lacks effective treatment.

AirID provides highly interaction-dependent biotinylation for analysis of protein–protein interaction.