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    1. Ecology

    Human disturbance increases spatiotemporal associations among mountain forest terrestrial mammal species

    Xueyou Li, William V Bleisch ... Xue-Long Jiang
    Human disturbance can push mammals together into more frequent encounters and associations.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural basis for diguanylate cyclase activation by its binding partner in Pseudomonas aeruginosa

    Gukui Chen, Jiashen Zhou ... Haihua Liang
    The diguanylate cyclase activity of SiaD is activated by its binding partner SiaC thourgh a dynamic mechanism of promoting the formation of active SiaD dimers.
    1. Cell Biology

    Non-canonical function of an Hif-1α splice variant contributes to the sustained flight of locusts

    Ding Ding, Jie Zhang ... Le Kang
    The long-distance flight of locusts is greatly facilitated by a muscle-abundantly expressed Hif-1α splice variant, which remains active in normoxia and scavenges flight-induced reactive oxygen species by upregulating the expression of DJ-1 (PARK 7).
    1. Neuroscience

    Coupling of pupil- and neuronal population dynamics reveals diverse influences of arousal on cortical processing

    Thomas Pfeffer, Christian Keitel ... Joachim Gross
    Spontaneous fluctuations in pupil-indexed arousal shape human cortical dynamics in a frequency-dependent and spatially diverse manner.
    1. Stem Cells and Regenerative Medicine

    Adult zebrafish Langerhans cells arise from hematopoietic stem/progenitor cells

    Sicong He, Jiahao Chen ... Jin Xu
    Adult zebrafish Langerhans cells are derived from hematopoietic stem/progenitor cells but not Erythro-myeloid progenitors.
    1. Ecology
    2. Evolutionary Biology

    Widespread mermithid nematode parasitism of Cretaceous insects

    Cihang Luo, George O Poinar ... Bo Wang
    Sixteen new mermithid nematodes associated with their insect hosts are discovered from mid-Cretaceous Kachin amber and they are more abundant in non-holometabolous insect hosts, revealing what appears to be a vanished history of nematodes parasitism.
    1. Structural Biology and Molecular Biophysics

    Molecular basis for N-terminal alpha-synuclein acetylation by human NatB

    Sunbin Deng, Buyan Pan ... Ronen Marmorstein
    The cryo-EM structure of the human N-terminal acetyltransferase NatB bound to a cognate N-terminal alpha-synuclein peptide reveals the molecular determinants of NatB-specific protein acetylation.
    1. Cell Biology
    2. Neuroscience

    Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain

    Ronit Ilouz, Varda Lev-Ram ... Susan S Taylor
    High-resolution, large-scale immunohistochemical mouse brain images showing global views of different brain regions, as well as cellular and subcellular details, identified distinct localization of PKA RIβ and RIIβ regulatory subunits that reveal functional differences.
    1. Neuroscience

    Enhancing precision in human neuroscience

    Stephan Nebe, Mario Reutter ... Gordon B Feld
    Measurement precision offers a comprehensive perspective on good scientific practices to improve reproducibility of research results by providing means to optimize design and analysis parameters (e.g. sample size, trial count, or sample heterogeneity) in accordance with the researcher’s goals.
    1. Structural Biology and Molecular Biophysics

    De novo design of a homo-trimeric amantadine-binding protein

    Jooyoung Park, Brinda Selvaraj ... David Baker
    The first successful de novo design of a homo-trimeric protein that binds a C3 symmetric small molecule larger than a metal ion is an advance for computational protein design.