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A high-throughput pipeline for the characterization of cortical connectivity in mouse and human cortex.

Heterozygous Nf1 knockout mice exhibit distinct dopaminergic phenotypes in vivo, as revealed by the genetically encoded dopamine sensor dLight1, patch clamp electrophysiology, optogenetics, and novel viral tools for morphological analysis.

Correlated magnetic resonance imaging and ultramicroscopy resolves macro- and microvasculature in glioma models and allows treatment monitoring of antiangiogenic therapy.

Compared to non-burn tissue, T cells in burn tissue have a pro-inflammatory rather than a homeostatic tissue-resident phenotype, and unconventional T cells in burn tissue have a higher cytotoxic capacity.

LPS pre-exposure is tissue protective during a subsequent lethal E. coli peritonitis by long-term modulation the bone marrow B-cell and neutrophil pool which affects neutrophil tissue damaging properties and therapeutic activation of Cxcr4 promotes tissue damage control during sepsis.

A detailed characterization of mouse ovary development using tissue clearing and 3D lightsheet imaging identifies ovary folding, specification of cortical and medullary domains, and ovary encapsulation as major hallmarks of ovary morphogenesis.

Combining a multineuron patch-clamp system with an automated pipette pressure and cleaning device enables efficient screening of synaptic connectivity in human brain slices and allows inter-individual comparison.

A computational strategy for extracting representative numerical features from 3D microscopy data enables in-depth quantitative analysis of cell and tissue organization through machine learning-driven data integration and context-guided visualization.

Spontaneous elongation of epithelial colonies is related to the orientation of the mean nematic cell elongation field, as shown and tested with experiments and theory.

A new tool for three-dimensional exploration of adult zebrafish neuroanatomy.