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    1. Developmental Biology

    Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6

    Yi Xin et al.
    Genetics, in vivo imaging, and unbiased chemical biology screens reveal that Trpv6 functions as a cellular quiescence regulator and delineates a Trpv6-mediated Ca2+ signaling pathway maintaining the quiescent state.
    1. Developmental Biology

    Antagonistic regulation by insulin-like peptide and activin ensures the elaboration of appropriate dendritic field sizes of amacrine neurons

    Jiangnan Luo et al.
    Afferent-derived factors control the elaboration of appropriate and robust sizes of dendritic arbors by dynamically modulating dendritic growth parameters.
    1. Developmental Biology
    2. Neuroscience

    Low FoxO expression in Drosophila somatosensory neurons protects dendrite growth under nutrient restriction

    Amy R Poe et al.
    The development of Drosophila somatosensory neurons is spared under nutrient deficiency so that they grow more dendrites and make animals more sensitive to environmental stimuli.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Sex-specific transcriptomic responses to changes in the nutritional environment

    M Florencia Camus et al.
    Male and female Drosophila share core metabolic responses to different nutritional environments, but show opposing patterns of nutrient-dependent reproductive regulation.
    1. Stem Cells and Regenerative Medicine
    2. Immunology and Inflammation

    The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor

    Xiaofei Yu et al.
    The transcription factor NFIL3 is essential for the development of a committed bone marrow precursor that gives rise to all known innate lymphoid cell lineages in mice.
    1. Cell Biology
    2. Computational and Systems Biology

    Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block

    Jakub Tomek et al.
    A computer model of human cardiomyocyte was produced and validated on independent datasets, overcoming shortcomings of its predecessors, also yielding broadly relevant insights and results on major ionic currents.
    1. Immunology and Inflammation

    Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema

    Ran You et al.
    The accumulation of carbon black nanoparticles in smokers' lungs causes sterile inflammation, double-strand DNA breaks and emphysema.
    1. Neuroscience

    Empathic pain evoked by sensory and emotional-communicative cues share common and process-specific neural representations

    Feng Zhou et al.
    Machine learning analyses reveal that the observation of acute pain inflictions and facial expressions of pain evoke shared pain-specific neural representations.
    1. Neuroscience

    Somatic and vicarious pain are represented by dissociable multivariate brain patterns

    Anjali Krishnan et al.
    Understanding others' pain is grounded in cognitive rather than sensory faculties.
    1. Microbiology and Infectious Disease

    Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration

    Malgorzata Broncel et al.
    Myristoylation of a secreted protein, identified in a global myristoylation analysis of the eukaryotic parasite Toxoplasma gondii, is important for host cell invasion.