240 results found
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A novel role for lipid droplets in the organismal antibacterial response

    Preetha Anand, Silvia Cermelli ... Steven P Gross
    Histones bound to lipid droplets inside cells offer protection against bacteria in flies, and possibly mice, thus suggesting a possible new innate immunity pathway.
    1. Microbiology and Infectious Disease

    The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria

    Robert Noble, Zóe Christodoulou ... Mario Recker
    The first comprehensive analysis of antigenic switching in the malaria-causing parasite Plasmodium falciparum provides new insights into the process that prevents individuals from acquiring immunity to the disease.
    1. Microbiology and Infectious Disease

    A serine sensor for multicellularity in a bacterium

    Arvind R Subramaniam, Aaron DeLoughery ... Yunrong Chai
    Biofilm formation by Bacillus subtilis relies on a sensing mechanism for the amino acid serine that does not depend on a dedicated protein or RNA.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Bacterial autolysins trim cell surface peptidoglycan to prevent detection by the Drosophila innate immune system

    Magda Luciana Atilano, Pedro Matos Pereira ... Sérgio Raposo Filipe
    To avoid recognition by the immune system, bacteria use autolysins to trim fragments of peptidoglycans that are exposed on the bacterial cell wall.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Cell-cycle dependent phosphorylation of yeast pericentrin regulates γ-TuSC-mediated microtubule nucleation

    Tien-chen Lin, Annett Neuner ... Elmar Schiebel
    Phosphorylation of Spc110 N-terminal domain encompassing conserved motifs and its interaction with conserved GCP3 N-terminal domain regulate the oligomerization of gamma-tubulin small complexes (γ-TuSCs).
    1. Physics of Living Systems

    Assembly principles of a unique cage formed by hexameric and decameric E. coli proteins

    Hélène Malet, Kaiyin Liu ... Irina Gutsche
    Cryo-electron microscopy uncovers molecular determinants of a unique symmetry mismatched macromolecular cage in E. coli.
    1. Microbiology and Infectious Disease

    Active invasion of bacteria into living fungal cells

    Nadine Moebius, Zerrin Üzüm ... Christian Hertweck
    Bacteria invade living fungal cells using secreted chitinolytic enzymes that allow for a traceless entry, as shown by microscopic snapshots.
    1. Microbiology and Infectious Disease

    Effective use of a horizontally-transferred pathway for dichloromethane catabolism requires post–transfer refinement

    Joshua K Michener, Aline A Camargo Neves ... Christopher J Marx
    Adapting bacteria to use an introduced metabolic pathway recapitulates natural mutations and offers a novel bioremediation strategy.
    1. Ecology
    2. Plant Biology

    Plant defense phenotypes determine the consequences of volatile emission for individuals and neighbors

    Meredith C Schuman, Silke Allmann, Ian T Baldwin
    Both the frequency of sesquiterpene-emitting individuals and the defense capacity of individual plants determine the consequences of sesquiterpene volatile emission for individuals and their neighbors in populations of the wild tobacco Nicotiana attenuata.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Juxtaposition of heterozygous and homozygous regions causes reciprocal crossover remodelling via interference during Arabidopsis meiosis

    Piotr A Ziolkowski, Luke E Berchowitz ... Ian R Henderson
    Heterozygosity changes the balance between interfering and non-interfering crossovers during Arabidopsis meiosis.

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