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Palmitoleic acid not only potentiates vancomycin killing of Gram-positive bacteria, but the insertion of palmitoleic acid into the membrane leads to the unexpected accumulation of membrane-bound cell wall precursors, representing a novel mechanism of action for unsaturated fatty acids.

Analysing Myosin II unipolar planar polarisation with high spatial and temporal resolution during Drosophila axis extension reveals how tissue boundaries drive polarized cell intercalation while limiting cell mixing.

The atomic structure of GtACR1 provides new insight into the chemical mechanism of natural light-gated anion membrane conductance, and enables its optimization for optogenetic photoinhibition of neuron firing.

Surface protein precursors traffic to lipoteichoic acid-rich septal membranes of Staphylococcus aureus for cleavage of their YSIRK-GXXS motif signal peptides and SecA-mediated translocation across the plasma membrane.

Single-cell time-lapse imaging and optogenetical gene recombination system uncovered that bacteria cells can overcome a deleterious genetic change of antibiotic resistance gene deletion depending on their environmental histories.

Analysis of suppressor mutants led to the identification of a novel signalling pathway that regulates peptidoglycan biosynthesis in Gram-positive bacteria.

Microbial populations are continuous along the gastrointestinal tract, with increased transmission in colorectal cancer and rheumatoid arthritis patients.

Step-wise processing of plant peptide hormone precursors by subtilisin-like proteinases in consecutive compartments of the secretory pathway is required for formation and secretion of the bioactive peptides.

MicroRNA-218 is required in both excitatory and inhibitory neurons of the developing hippocampus to regulate intrinsic and network excitability.