Browse the search results

Page 2 of 21
    1. Chromosomes and Gene Expression
    2. Stem Cells and Regenerative Medicine

    TERRA regulate the transcriptional landscape of pluripotent cells through TRF1-dependent recruitment of PRC2

    Rosa María Marión, Juan J Montero ... Maria A Blasco
    Telomeric TRF1 controls the transcriptional programmes of pluripotent stem cells by recruiting PRC2 to pluripotency and differentiation genes by controlling the expression of those gene sites and the binding of TERRA RNAs to them.
    1. Cancer Biology
    2. Cell Biology

    NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans

    Collin Yvès Ewald, John M Hourihan ... Nancy E Hynes
    Genetic analysis reveals NADPH oxidase generated reactive oxygen species as signals to re-establish cellular homeostasis during aging via activating a transcriptional response.
    1. Neuroscience

    A cell atlas of the chick retina based on single-cell transcriptomics

    Masahito Yamagata, Wenjun Yan, Joshua R Sanes
    A molecular atlas of the chick retina provides a comprehensive classification and characterization of 136 cell types, yielding novel insights into retinal structure, function, development, and evolution.
    1. Cell Biology

    Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes

    Roberto Villaseñor, Hidenori Nonaka ... Marino Zerial
    Cells package active receptors in endosomes at fairly constant amounts and can determine different cell-fate decisions by regulating the number and lifetime of receptor packages.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Olfactory detection of viruses shapes brain immunity and behavior in zebrafish

    Aurora Kraus, Benjamin Garcia ... Irene Salinas
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Inadequate
    1. Cell Biology
    2. Computational and Systems Biology

    Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis

    Alison L Kearney, Dougall M Norris ... James G Burchfield
    Akt phosphorylates insulin receptor substrate to engage negative feedback and limit signal propagation.
    1. Cell Biology

    GTPase activating protein DLC1 spatio-temporally regulates Rho signaling

    Max Heydasch, Lucien Hinderling ... Olivier Pertz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    Lacticaseibacillus rhamnosus P118 enhances host tolerance to Salmonella infection by promoting microbe-derived indole metabolites

    Baikui Wang, Xianqi Peng ... Min Yue
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Immunology and Inflammation

    Human thymopoiesis produces polyspecific CD8+ α/β T cells responding to multiple viral antigens

    Valentin Quiniou, Pierre Barennes ... David Klatzmann
    The thymic selection of the human T-cell receptor repertoire releases polyspecific receptors with the ability to recognize and respond to peptides from unrelated viruses.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes

    Edhriz Siraliev-Perez, Jordan TB Stariha ... John Sondek
    PLC-γ isozymes are activated by a combination of receptor engagement and membrane proximity.
Newer Older