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    1. Cell Biology
    2. Microbiology and Infectious Disease

    Basalin is an evolutionarily unconstrained protein revealed via a conserved role in flagellum basal plate function

    Samuel Dean, Flavia Moreira-Leite, Keith Gull
    Basalins are intrinsically disordered proteins with astonishingly high-sequence divergence that are essential for building the transition zone basal plate and for proper central pair nucleation.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor

    Harriet Lane-Serff, Paula MacGregor ... Mark Carrington
    The ligand specificity and expression profile of the haptoglobin-haemoglobin receptor has diversified throughout the evolution of trypanosomes.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor

    Harriet Lane-Serff, Paula MacGregor ... Matthew K Higgins
    The structure of the trypanosome haptoglobin-haemoglobin receptor bound to its ligand reveals the molecular basis for ligand recognition in innate immunity and identifies molecular determinants that aid efficient uptake.
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