354 results found
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    A twist defect mechanism for ATP-dependent translocation of nucleosomal DNA

    Jessica Winger et al.
    Based on its nucleotide-bound state, the Chd1 chromatin remodeler can locally alter DNA twist on the nucleosome, which either pulls in or expels ~1 bp of DNA at the internal SHL2 binding site.
    1. Cancer Biology
    2. Human Biology and Medicine

    Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression

    Viviana Anelli et al.
    Transformation mediated by oncogenic BRAF requires transcriptional activation of TWIST at the earliest stage of neoplastic transformation.
    1. Cell Biology

    Cell Biology: New twists in the unfolded protein response

    Benedict C S Cross, David Ron
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    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Motor Proteins: A surprising twist

    Nikta Fakhri, Christoph F Schmidt
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    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Virus Evolution: A new twist in measuring mutation rates

    Bartram L Smith, Claus O Wilke
    The influenza virus mutates faster than we previously thought.
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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome

    Camilla S Teng et al.
    Sequential live imaging of abnormal skull bone fusion in zebrafish reveals a deeply conserved role of two transcription factors, Twist1 and Tcf12, in regulating stem cell activity during growth of the skull.
    1. Developmental Biology

    Heart Morphogenesis: Twists and turns

    Emily S Noël, Jeroen Bakkers
    Computational modelling of the heart tube during development reveals the interplay between tissue asymmetry and growth that helps our hearts take shape.
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  1. Scientific Publishing: A new twist on peer review

    Mark Patterson, Randy Schekman
    eLife is conducting a trial in which authors will decide how to respond to the issues raised during peer review.
    Editorial
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