Secretion and fibrillogenesis of collagen-I are separately controlled molecular pathways in the fibroblast, where surprisingly endocytic recycling is required for fibril formation and is increased in fibrotic fibroblasts.
Nicolas Flaugnatti, Loriane Bader ... Melanie Blokesch
Capsular polysaccharides of Acinetobacter baumannii regulate type VI secretion system activity, balancing self-protection with interbacterial competitiveness.
Rosalyn W Sayaman, Masaru Miyano ... Mark A LaBarge
Breast luminal epithelial cells are the hotspots of aging-associated changes, which prime aged epithelia for oncogenic gene activation and may explain individual differences in breast cancer susceptibility due to the aging-associated increase in gene expression variances in luminal epithelia.
Common mouse models of polycystic ovary syndrome (PCOS) have variable ability to recapitulate the increased GnRH pulse generator frequency thought to exist in women with PCOS.