Prefrontal cortex plays a leading role in sequential decisions compared to posterior parietal cortex and relies on nonlinear integration of sensory and mnemonic information for decision formation.
Yiyi Chen, Laimdota Zizmare ... Christoph Trautwein
Targeted manipulations on organotypic cultures show that the retina switches between at least four different metabolic pathways, each with different yields and kinetics, to dynamically adapt to momentaneous energy needs.
Nishal Pradeepbhai Shah, AJ Phillips ... EJ Chichilnisky
A novel method of electrical stimulation to precisely control neural activity for sensory restoration exhibits improvements in visual stimulus reconstruction, enables efficient hardware design, and extends to naturalistic conditions.
Hundreds of proteins are involved in the DNA damage response but only three sensors for DSB were known but now SIRT6 is identified as a fourth DSB sensor.
Sara N Mouton, David J Thaller ... Liesbeth M Veenhoff
In mitotically aging yeast cells, the cytosol acidifies, the distances between the organellar membranes decrease dramatically, but crowding on the scale of the average size protein is relatively stable.
Exosomes from cancer-associated fibroblasts enhance the "Warburg effect" in tumors and contain de novo metabolites that can contribute to the entire compendia of central carbon metabolism within cancer cells.
Behavioral and computational results show that the perception of our body as our own depends on Bayesian probabilistic reasoning that take into account the variations in sensory uncertainty when integrating visual and somatosensory cues.