Biochemical and structural biological analyses show how bacteria can recognize hormones that control the production of important secondary metabolites such as antiparasitics and antibiotics.
The readiness potential—a long-established neural precursor of voluntary action claimed to precede the onset of the conscious decision to move—is absent, or at least significantly reduced, for deliberate decisions.
The different laminar profiles observed across the cortical depth for multisensory and attentional influences indicate partly distinct neural circuitries of information-flow control.
Hannes Ruge, Theo AJ Schäfer ... Uta Wolfensteller
Ventro-lateral prefrontal cortex codes novel rules starting from their first-time implementation right after instruction while early consolidation is channeled through increasing cooperation with the anterior striatum.
Caitlin N Spaulding, Henry Louis Schreiber IV ... Edward H Egelman
The helical rod structure and dynamic spring-like properties of the type 1 pilus are evolutionarily fine-tuned for functioning in host-pathogen interactions during urinary tract infection and gut colonization.
Ute I Scholl, Gabriel Stölting ... Richard P Lifton
A novel Mendelian disease featuring early-onset hypertension is caused by a recurrent gain of function mutation in CACNA1H, which encodes the voltage-gated calcium channel Cav3.2.
The Aire-dependent genes show a preference for short 3’UTR transcript isoforms resulting in the escape from the post-transcriptional repression mediated by miRNAs in medullary thymic epithelial cells.