7,104 results found
    1. Developmental Biology
    2. Neuroscience

    A cellular and molecular analysis of SoxB-driven neurogenesis in a cnidarian

    Eleni Chrysostomou, Hakima Flici ... Uri Frank
    SoxB genes are sequentially expressed in cnidarian neurogenesis.
    1. Biochemistry and Chemical Biology

    Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones

    Iti Kapoor, Philip Olivares, Satish K Nair
    Biochemical and structural biological analyses show how bacteria can recognize hormones that control the production of important secondary metabolites such as antiparasitics and antibiotics.
    1. Neuroscience

    Neural precursors of decisions that matter—an ERP study of deliberate and arbitrary choice

    Uri Maoz, Gideon Yaffe ... Liad Mudrik
    The readiness potential—a long-established neural precursor of voluntary action claimed to precede the onset of the conscious decision to move—is absent, or at least significantly reduced, for deliberate decisions.
    1. Neuroscience

    Resolving multisensory and attentional influences across cortical depth in sensory cortices

    Remi Gau, Pierre-Louis Bazin ... Uta Noppeney
    The different laminar profiles observed across the cortical depth for multisensory and attentional influences indicate partly distinct neural circuitries of information-flow control.
    1. Evolutionary Biology

    Environmental response in gene expression and DNA methylation reveals factors influencing the adaptive potential of Arabidopsis lyrata

    Tuomas Hämälä, Weixuan Ning ... Outi Savolainen
    Environmentally responsive genes evolve under strong selective constraint in Arabidopsis lyrata.
    1. Neuroscience

    Neural representation of newly instructed rule identities during early implementation trials

    Hannes Ruge, Theo AJ Schäfer ... Uta Wolfensteller
    Ventro-lateral prefrontal cortex codes novel rules starting from their first-time implementation right after instruction while early consolidation is channeled through increasing cooperation with the anterior striatum.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions

    Caitlin N Spaulding, Henry Louis Schreiber IV ... Edward H Egelman
    The helical rod structure and dynamic spring-like properties of the type 1 pilus are evolutionarily fine-tuned for functioning in host-pathogen interactions during urinary tract infection and gut colonization.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism

    Ute I Scholl, Gabriel Stölting ... Richard P Lifton
    A novel Mendelian disease featuring early-onset hypertension is caused by a recurrent gain of function mutation in CACNA1H, which encodes the voltage-gated calcium channel Cav3.2.
    1. Microbiology and Infectious Disease

    Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with UTIs

    Anna Sintsova, Arwen E Frick-Cheng ... Harry Mobley
    Conserved transcriptomic profile of uropathogenic E. coli in patients identifies an infection-specific metabolic state.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Aire-dependent genes undergo Clp1-mediated 3’UTR shortening associated with higher transcript stability in the thymus

    Clotilde Guyon, Nada Jmari ... Matthieu Giraud
    The Aire-dependent genes show a preference for short 3’UTR transcript isoforms resulting in the escape from the post-transcriptional repression mediated by miRNAs in medullary thymic epithelial cells.

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