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Page 2 of 1,099
    1. Developmental Biology
    2. Immunology and Inflammation

    The extraembryonic serosa is a frontier epithelium providing the insect egg with a full-range innate immune response

    Chris G C Jacobs, Herman P Spaink, Maurijn van der Zee
    Contrary to the current perception, insect eggs are very capable of defending themselves against pathogens.
    1. Immunology and Inflammation

    Protective function and durability of mouse lymph node-resident memory CD8+ T cells

    Scott M Anthony, Natalija Van Braeckel-Budimir ... John T Harty
    Repeated antigen encounters alter the transcriptional state and function of lymph node-resident memory CD8+ T cells to mediate improved immunity against viral infection.
    1. Cancer Biology
    2. Computational and Systems Biology

    Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy

    Jonathan Rodriguez, Abdon Iniguez ... Richard A Van Etten
    A physiological mathematical model of chronic myeloid leukemia, validated by experiments in transgenic mice and clinical data, identifies mechanisms underlying the response to tyrosine kinase inhibitor therapy, predicts biomarkers of primary resistance, and suggests new strategies to improve treatment outcomes.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction

    Gurunathan Laxmikanthan, Chen Xu ... Gregory D Van Duyne
    The structure of a multi-protein DNA recombination reaction intermediate reveals how regulation is achieved by protein-mediated DNA wrapping around a core enzyme-substrate complex.
    1. Neuroscience

    Towards biologically plausible phosphene simulation for the differentiable optimization of visual cortical prostheses

    Maureen van der Grinten, Jaap de Ruyter van Steveninck ... Yağmur Güçlütürk
    The provided framework based on biological models and clinical literature can aid in the optimization of visual cortical prostheses through computational or behavioral simulation experiments, serving as a flexible tool for computational, clinical, and behavioral neuroscientists working on visual neuroprosthetics.
    1. Neuroscience

    In vivo assessment of the neural substrate linked with vocal imitation accuracy

    Julie Hamaide, Kristina Lukacova ... Annemie Van der Linden
    Song learning accuracy can be predicted and traced in the structural properties of the brains of juvenile male zebra finches already at 20 days post-hatching.
    1. Neuroscience

    Vicarious reward unblocks associative learning about novel cues in male rats

    Sander van Gurp, Jochen Hoog ... Marijn van Wingerden
    Rats learn to interpret cues predicting rewards delivered to social partners as valuable, but only if social information exchange is possible.
    1. Ecology

    Role of immigrant males and muzzle contacts in the uptake of a novel food by wild vervet monkeys

    Pooja Dongre, Gaëlle Lanté ... Erica van de Waal
    New immigrants triggered fast uptake of a novel food in groupmates, who obtained information about it through muzzle contacts, opening up new questions about the role of dispersers in information flow around a population.
    1. Genetics and Genomics
    2. Plant Biology

    A gene horizontally transferred from bacteria protects arthropods from host plant cyanide poisoning

    Nicky Wybouw, Wannes Dermauw ... Thomas Van Leeuwen
    The enzyme that allows some mites and insects to detoxify the hydrogen cyanide produced by plants has been identified.
    1. Microbiology and Infectious Disease

    A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites

    Ben C L van Schaijk, Ivo H J Ploemen ... Robert W Sauerwein
    The preclinical evaluation of a malaria genetically attenuated parasite vaccine candidate suggests that it is both safe and effective.