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    1. Ecology
    2. Evolutionary Biology

    Ecological and social pressures interfere with homeostatic sleep regulation in the wild

    J Carter Loftus, Roi Harel ... Margaret C Crofoot
    Collective dynamics and site familiarity, but not the recent history of sleep and activity, shape sleep patterns in a wild social primate.
    1. Biochemistry and Chemical Biology

    High-throughput proteomics of nanogram-scale samples with Zeno SWATH MS

    Ziyue Wang, Michael Mülleder ... Markus Ralser
    Zeno SWATH MS, a novel data-independent acquisition technique in proteomics, which by facilitating sensitive detection in high-throughput experiments with low sample amounts, mitigates current bottlenecks of high-throughput proteomics.
    1. Neuroscience

    Optimization of energy state transition trajectory supports the development of executive function during youth

    Zaixu Cui, Jennifer Stiso ... Theodore D Satterthwaite
    Structural network topology develops during adolescence to facilitate activation of the fronto-parietal executive system with lower theoretical energetic cost.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    CCL28 modulates neutrophil responses during infection with mucosal pathogens

    Gregory T Walker, Araceli Perez-Lopez ... Manuela Raffatellu
    Chemokine CCL28 plays a key role in shaping neutrophil responses during intestinal Salmonella infection and lung Acinetobacter infection.
    1. Immunology and Inflammation

    SARS-CoV-2 uses CD4 to infect T helper lymphocytes

    Natalia S Brunetti, Gustavo G Davanzo ... Alessandro S Farias
    The infection of T helper lymphocytes by SARS-CoV-2, mediated via the CD4 molecule, alters cellular function and enhances expression of the anti-inflammatory cytokine IL-10, potentially impairing immune response in individuals with COVID-19.
    1. Neuroscience

    Controllability boosts neural and cognitive signatures of changes-of-mind in uncertain environments

    Marion Rouault, Aurélien Weiss ... Valentin Wyart
    Task controllability manipulations reveal that information seeking is associated with reduced confidence and active hypothesis testing, as well as stronger neurophysiological correlates of attention and arousal.
    1. Microbiology and Infectious Disease

    A Plasmodium falciparum MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatin

    Maneesh Kumar Singh, Victoria Ann Bonnell ... Celia RS Garcia
    Multi-omic analyses reveal that the chromatin-associated microrchidia protein, MORC (PF3D7_1468100), at the blood stage of the human malaria parasite, Plasmodium falciparum, interacts with a range of nuclear proteins.
    1. Ecology

    Genomic adaptations in information processing underpin trophic strategy in a whole-ecosystem nutrient enrichment experiment

    Jordan G Okie, Amisha T Poret-Peterson ... James J Elser
    Trait-based metagenomic analysis of an ecosystem fertilization experiment shows that genomic traits that affect the costs and rates of biochemical information-processing mediate community assembly.
    1. Ecology
    2. Epidemiology and Global Health

    Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence

    Cara E Brook, Mike Boots ... Anieke van Leeuwen
    Bats' uniquely robust innate antiviral immune defenses select for faster transmitting viruses likely to generate extreme virulence upon spillover to secondary hosts with immune systems divergent from those of bat.
    1. Microbiology and Infectious Disease

    BipA exerts temperature-dependent translational control of biofilm-associated colony morphology in Vibrio cholerae

    Teresa del Peso Santos, Laura Alvarez ... Felipe Cava
    Vibrio cholerae uses a conserved ribosome assembly factor to repress biofilm formation at low temperatures.