119 results found
    1. Cell Biology
    2. Developmental Biology

    Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2

    Pierluigi Scerbo, Leslie Marchal, Laurent Kodjabachian
    Degradation and asymmetric inheritance during cell division of a core pluripotency regulator contributes to lineage commitment in the early Xenopus embryo.
    1. Neuroscience

    Neuroanatomy of a hydrothermal vent shrimp provides insights into the evolution of crustacean integrative brain centers

    Julia Machon, Jakob Krieger ... Steffen Harzsch
    A neuroanatomical analysis of Rimicaris exoculata provides insights into these animal’s brain architecture to illustrate possible adaptations to the hydrothermal vent habitat with its extreme physicochemical conditions.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Abundant toxin-related genes in the genomes of beneficial symbionts from deep-sea hydrothermal vent mussels

    Lizbeth Sayavedra, Manuel Kleiner ... Jillian M Petersen
    Beneficial symbiotic bacteria encode an exceptional number of toxin-related genes that are all expressed by the symbionts in the host, supporting their key role in host-microbe interactions.
    1. Neuroscience

    Brain Evolution: Adaptations to extreme conditions

    Barbara S Beltz
    The brain architecture of shrimp living in deep-sea vents provides clues to how these organisms have adapted to extreme living.
    Version of Record
    Insight
    1. Developmental Biology

    Regionally distinct trophoblast regulate barrier function and invasion in the human placenta

    Bryan Marsh, Yan Zhou ... Robert Blelloch
    Single cell RNA-sequencing of distinct regions of the human placenta identifies a smooth chorion-specific cytotrophoblast population responsible for unique functions of the smooth chorion, including acting as a barrier and restricting invasion.
    1. Genetics and Genomics

    Single cell transcriptional signatures of the human placenta in term and preterm parturition

    Roger Pique-Regi, Roberto Romero ... Nardhy Gomez-Lopez
    Parturition gene regulation across multiple cell-types and placental compartments is deciphered at single cell resolution, highlighting the common role of the NFKB pathway in both term and preterm birth.
    1. Evolutionary Biology

    Antibacterial gene transfer across the tree of life

    Jason A Metcalf, Lisa J Funkhouser-Jones ... Seth R Bordenstein
    Parallel horizontal gene transfer has spread a bacteriolytic gene family to all domains of life, and has bestowed a niche-transcending adaptation in recipients that must deploy antibacterial molecules to survive in a bacterial world.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Insight into the evolution of microbial metabolism from the deep-branching bacterium, Thermovibrio ammonificans

    Donato Giovannelli, Stefan M Sievert ... Costantino Vetriani
    The genome of Thermovibrio ammonificans encodes ancestral pathways (e.g., hydrogen oxidation) and more recently acquired ones (e.g., nitrate reduction) and a hybrid pathway for CO2 fixation.
    1. Ecology
    2. Evolutionary Biology

    Point of View: Managing a sustainable deep-sea ‘blue economy’ requires knowledge of what actually lives there

    Adrian G Glover, Helena Wiklund ... Thomas G Dahlgren
    High-throughput, integrative taxonomy has a crucial role to play in ensuring that the resources in our oceans are managed and developed in a sustainable manner.
    1. Evolutionary Biology

    Evolutionary transcriptomics implicates new genes and pathways in human pregnancy and adverse pregnancy outcomes

    Katelyn Mika, Mirna Marinić ... Vincent J Lynch
    Comparative studies of gene expression in the uterus during pregnancy identifies new genes important for pregnancy and associated with complications such as preterm birth.

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