4,927 results found
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Host-selected mutations converging on a global regulator drive an adaptive leap towards symbiosis in bacteria

    M Sabrina Pankey et al.
    Selective forces imposed by the squid animal host drive rapid adaptation of non-native Vibrio fischeri bacteria through convergent mutations of large effect, unmasking preexisting coordinated regulation of symbiosis.
    1. Microbiology and Infectious Disease

    BipA exerts temperature-dependent translational control of biofilm-associated colony morphology in Vibrio cholerae

    Teresa del Peso Santos et al.
    Vibrio cholerae uses a conserved ribosome assembly factor to repress biofilm formation at low temperatures.
    1. Microbiology and Infectious Disease

    The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching

    Brittany L Carroll et al.
    In situ structures of the flagellar motors genetically docked in CCW and CW rotational states reveal major rearrangement that facilitates rotational switch in Vibrio alginolyticus..
    1. Microbiology and Infectious Disease

    The host exosome pathway underpins biogenesis of the human cytomegalovirus virion

    Declan L Turner et al.
    The HCMV virion envelope is derived from the host exosome membrane, and exosome machinery and export pathways facilitate virion egress.
    1. Microbiology and Infectious Disease

    Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae

    Noémie Matthey et al.
    Whole-genome sequencing reveals the remarkable extent of horizontally moving genetic material in naturally competent Vibrio cholerae after a prey-killing DNA acquisition process.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Human axial progenitors generate trunk neural crest cells in vitro

    Thomas JR Frith et al.
    Pluripotent stem cell differentiation provides insight into how neural crest subtypes of distinct axial identity are patterned in human embryos.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Pervasive transcription fine-tunes replication origin activity

    Tito Candelli et al.
    The pervasive transcription environment alters the efficiency of firing of replication origins, which are 'protected' by roadblock termination due to origin recognition complex (ORC) and pre-RC complexes.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Regulation by the quorum sensor from Vibrio indicates a receptor function for the membrane anchors of adenylate cyclases

    Stephanie Beltz et al.
    A canonical class III adenylate cyclase with a membrane anchor of six transmembrane spans is regulated by a receptor of similar design, the quorum-sensing receptor from Vibrio harveyi.
    1. Microbiology and Infectious Disease

    Dominant Vibrio cholerae phage exhibits lysis inhibition sensitive to disruption by a defensive phage satellite

    Stephanie G Hays, Kimberley D Seed
    Genetic and molecular analyses identify and characterize an evolutionary battle over lysis timing wherein a bacteriophage delays lysis through lysis inhibition while a defensive phage satellite accelerates lysis.
    1. Structural Biology and Molecular Biophysics

    A facile approach for the in vitro assembly of multimeric membrane transport proteins

    Erika A Riederer et al.
    Methodology for the in vitro assembly of multimeric membrane proteins and the utility of the approach for generating heteromeric variants of homo-multimeric proteins is described.

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