As the function of membrane proteins is often influenced by its membrane environment the presented combinatorial approach is of great value for the investigation of membrane protein complexes in natural or even manipulated lipid bilayers.
Spizellomycespunctatusis a genetically tractable chytrid and model organism for comparative cell biology for understanding evolution of the cell cycle, actin dynamics, and cellularization in fungi and early eukaryotes.
Data-driven systems biology models of signaling predict cellular response to untested perturbations and can nominate drug combinations to overcome drug resistance in cancer cells.
eLife editors trial a new approach to including more early-stage researchers in peer review for papers in the fields of Genomics and Evolutionary Biology.