969 results found
    1. Computational and Systems Biology
    2. Ecology

    Data-driven identification of potential Zika virus vectors

    Michelle V Evans et al.
    Data-driven methods predict over 35 mosquitoes are potential vectors of Zika virus, suggesting a larger geographic area and a greater human population is at risk of infection.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Mapping global environmental suitability for Zika virus

    Jane P Messina et al.
    A global map of environmental suitability for Zika virus and the estimated population living at potential risk can help refine public health guidelines, travel advisories and intervention strategies at a crucial time in the global emergence of this arbovirus.
    1. Biophysics and Structural Biology

    The near-atomic cryoEM structure of a flexible filamentous plant virus shows homology of its coat protein with nucleoproteins of animal viruses

    Xabier Agirrezabala et al.
    The high-resolution structure of a filamentous flexible plant virus shows that there is structural homology between its coat protein and the nucleoproteins of an unrelated group of enveloped RNA animal viruses.
    1. Ecology
    2. Genomics and Evolutionary Biology

    Viral dark matter and virus–host interactions resolved from publicly available microbial genomes

    Simon Roux et al.
    From public microbial genomes, VirSorter revealed 12,498 viral genome sequences that expand the map of the global virosphere and whose analyses improve understanding of viral taxonomy, evolution and virus-host interactions.
    1. Ecology
    2. Microbiology and Infectious Disease

    Ecology and evolution of viruses infecting uncultivated SUP05 bacteria as revealed by single-cell- and meta-genomics

    Simon Roux et al.
    Single-cell amplified genome sequencing uncovers virus-host interactions in uncultivated sulfur-oxidizing bacteria with relevance to coupled biogeochemical cycling in marine oxygen minimum zones.
    1. Biophysics and Structural Biology
    2. Microbiology and Infectious Disease

    Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates

    Tijana Ivanovic et al.
    Long-lived intermediate states formed by glycoprotein catalysts are an essential part of the process used by influenza virus particles to infect cells.
    1. Biochemistry
    2. Microbiology and Infectious Disease

    RNA structures that resist degradation by Xrn1 produce a pathogenic Dengue virus RNA

    Erich G Chapman et al.
    The Dengue virus contains discretely folded RNA structures that confer the ability to resist a powerful host cell enzyme and produce a disease-inducing noncoding RNA.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Updates to the zoonotic niche map of Ebola virus disease in Africa

    David M Pigott et al.
    Building on previous work (Pigott et al. 2014), estimates of areas of potential transmission of Ebola virus are revised and updated to provide a contemporary map for use by researchers and policymakers.
    1. Cancer Biology
    2. Genes and Chromosomes

    MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs

    C David Wood et al.
    Epstein-Barr virus controls B-cell growth and survival through large-scale reorganization of the enhancers of the MYC and BCL2L11 genes, and may promote MYC translocations as a result.
    1. Genomics and Evolutionary Biology
    2. Microbiology and Infectious Disease

    Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses

    Michael B Schulte et al.
    A mathematical model that combines stochasticity and spatial structure describes the dynamics of the viral population during an infection cycle, and fitting the model to RNA and virus abundances over time shows that poliovirus follows a geometric replication mode.

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