128 results found
    1. Cell Biology

    Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells

    Lorena Benedetti, Jonathan S Marvin ... Pietro De Camilli
    eMags is an engineered photodimerizer pair for optogenetic modulation in mammalian cells that is especially suited for the manipulation of intracellular processes occurring in small volumes or subcellular organelles.
    1. Neuroscience

    Suppression weakens unwanted memories via a sustained reduction of neural reactivation

    Ann-Kristin Meyer, Roland G Benoit
    Intentionally preventing the retrieval of an unwanted memory hinders future attempts to reactivate the memory’s neural representation and causes a reduction in the vividness with which it can be recalled.
    1. Neuroscience

    DMT alters cortical travelling waves

    Andrea Alamia, Christopher Timmermann ... Robin L Carhart-Harris
    Psychedelics induce a pattern of cortical activity very similar to the one observed during visual perception, despite participants had shut eyes.
    1. Neuroscience

    Revealing the neural fingerprints of a missing hand

    Sanne Kikkert, James Kolasinski ... Tamar R Makin
    The brain continues to represent individual fingers in primary somatosensory cortex decades after the amputation of a hand, indicating that cortical maps do not require ongoing sensory input from the body.
    1. Neuroscience

    Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia

    Merlin Monzel, Pitshaporn Leelaarporn ... Cornelia McCormick
    The autobiographical memory deficits seen in aphantasia are reflected by altered activation and connectivity patterns of the hippocampus and occipital cortex, corroborating the strong link between memory and mental imagery.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Decoding the activated stem cell phenotype of the neonatally maturing pituitary

    Emma Laporte, Florian Hermans ... Hugo Vankelecom
    The neonatally maturing pituitary harbors an activated stem cell compartment and shows prominent regenerative capacity, as revealed by single-cell transcriptomic profiling and in vitro (organoid) and in vivo (mouse) exploration.
    1. Neuroscience

    Distinct neural mechanisms underlie subjective and objective recollection and guide memory-based decision making

    Yana Fandakova, Elliott G Johnson, Simona Ghetti
    Neural substrates of objective vs. subjective memory states can be distinguished, including their role in supporting decisions aimed at optimizing performance.
    1. Neuroscience

    Distinct neural mechanisms underlie the success, precision, and vividness of episodic memory

    Franziska R Richter, Rose A Cooper ... Jon S Simons
    Combining fMRI with continuous model-based measures of retrieval enables the behavioral and neural dissociation of multiple components of episodic memory.
    1. Neuroscience

    Obtaining and maintaining cortical hand representation as evidenced from acquired and congenital handlessness

    Daan B Wesselink, Fiona MZ van den Heiligenberg ... Tamar R Makin
    fMRI results show that despite arm amputation, and varying degrees of phantom sensations, canonical hand representation in primary somatosensory cortex is largely maintained.
    1. Neuroscience

    The pupillary light response as a physiological index of aphantasia, sensory and phenomenological imagery strength

    Lachlan Kay, Rebecca Keogh ... Joel Pearson
    Physiological evidence shows that the pupillary response to imagined light can be used to index the strength and vividness of an individual’s visual imagery and as a new tool for confirming aphantasia.

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