2,001 results found
    1. Developmental Biology
    2. Neuroscience

    Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling

    Hao Wu, John Williams, Jeremy Nathans
    The first survey of the complete morphologies of nerve endings in the skin of mice has revealed enormous structural diversity.
    1. Neuroscience

    Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster

    César S Mendes, Imre Bartos ... Richard S Mann
    Novel imaging experiments suggest that fruit flies modify their neural circuitry for walking at slow, medium and fast speeds, and that proprioception is not essential for coordinated walking.
    1. Neuroscience

    Changing the responses of cortical neurons from sub- to suprathreshold using single spikes in vivo

    Verena Pawlak, David S Greenberg ... Jason ND Kerr
    Changing the order in which presynaptic and postsynaptic cells are repeatedly activated can change what a mammalian visual cortex neuron communicates to downstream neurons.
    1. Cell Biology

    Time line of redox events in aging postmitotic cells

    Nicolas Brandes, Heather Tienson ... Ursula Jakob
    A sudden fall in the levels of the coenzyme NADPH within cells could have a central role in the process of aging.
    1. Neuroscience

    Hierarchical organization of context in the hippocampal episodic code

    Susumu Takahashi
    Neurons in the hippocampus modulate the rates at which they fire, and the locations in which they fire, so as to encode the information that is central to forming memories about personal experiences.
    1. Cell Biology
    2. Neuroscience

    AP2 hemicomplexes contribute independently to synaptic vesicle endocytosis

    Mingyu Gu, Qiang Liu ... Erik M Jorgensen
    A protein complex that enables cells to transport substances across their membranes, and that typically consists of four subunits, can also function as two hemicomplexes, each with two subunits.
    1. Cell Biology

    Intraflagellar transport drives flagellar surface motility

    Sheng Min Shih, Benjamin D Engel ... Ahmet Yildiz
    The transport of proteins along flagellar microtubules generates the force that enables flagella to propel cells across surfaces.
    1. Plant Biology

    Plant Biology: When the time is ripe

    Siobhan M Brady
    Version of Record
    Insight
    1. Evolutionary Biology
    2. Cancer Biology

    Evolutionary dynamics of cancer in response to targeted combination therapy

    Ivana Bozic, Johannes G Reiter ... Martin A Nowak
    A study that models the evolution of drug resistance in tumors reveals that drugs are more effective when given in combination than sequentially, and that cure is much more likely when the drugs target different pathways.
    1. Stem Cells and Regenerative Medicine
    2. Microbiology and Infectious Disease

    Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni

    Bo Wang, James J Collins III, Phillip A Newmark
    Cells that give rise to the infectious form of parasitic flatworms called schistosomes show similar patterns of gene expression to stem cells in free-living flatworms.

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