1,317 results found
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Human DNA2 possesses a cryptic DNA unwinding activity that functionally integrates with BLM or WRN helicases

    Cosimo Pinto et al.
    The nuclease of hDNA2 limits its processive DNA unwinding capacity; the helicase function becomes stimulatory when hDNA2 is in complex with BLM or WRN helicase to degrade dsDNA.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

    William Wan et al.
    Cryo-electron tomography reveals the structure and arrangement of the VP40 matrix protein lattice that mediates the formation of Ebola and Marburg virus particles.
    1. Cell Biology

    Competition between kinesin-1 and myosin-V defines Drosophila posterior determination

    Wen Lu et al.
    Posterior determination of Drosophila oocyte is defined by competition between kinesin-1 removing posterior determinants from the cortex and myosin-V anchoring them.
    1. Cell Biology
    2. Developmental Biology

    Ingression-type cell migration drives vegetal endoderm internalisation in the Xenopus gastrula

    Jason WH Wen, Rudolf Winklbauer
    The cellular behaviours that underlie the internalization of the multilayered endoderm anlage in Xenopus laevis link the ancestral mode of vertebrate gastrulation to common, epithelial-based mechanisms of gastrulation in non-vertebrate animals.
    1. Immunology and Inflammation

    The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold

    Zhengpeng Wan et al.
    The B cell receptors of naïve B cells need higher levels of mechanical force to be fully activated than those of memory B cells.
    1. Neuroscience

    Synchronous and asynchronous modes of synaptic transmission utilize different calcium sources

    Hua Wen et al.
    The delayed-onset of asynchronous transmitter release seen in neurons that fire repeatedly is triggered by a different source of calcium from that which triggers synchronous transmitter release.
    1. Ecology

    Increasing plant diversity with border crops reduces insecticide use and increases crop yield in urban agriculture

    Nian-Feng Wan et al.
    Plant diversification can make an important contribution to ecological intensification and the sustainable use of associated ecosystem services in an urban ecosystem.
    1. Neuroscience

    Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD+ in axon regeneration

    Kyung Won Kim et al.
    A function-based genetic screen using the Caenorhabditis elegans axotomy model identifies new regulators and an inhibitory role for NAD+ in axon regeneration, expanding the understanding of axon injury responses and regeneration.
    1. Ecology
    2. Evolutionary Biology

    Disentangling strictly self-serving mutations from win-win mutations in a mutualistic microbial community

    Samuel Frederick Mock Hart et al.
    Whereas partner-serving phenotype is intuitively quantified as benefit release rate, molecular genetics revealed an example where this thinking fails, motivating a more general metric.

Refine your results by:

Type
Research categories