474 results found
    1. Developmental Biology and Stem Cells
    2. Physics of Living Systems

    Gene-free methodology for cell fate dynamics during development

    Francis Corson, Eric D Siggia
    Mathematical methods based on geometry that directly embody the developmental concepts of competency, commitment, and determination provide succinct descriptions of morphogenesis and allow quantitative predictions from fits to sparse genetic data in Caenorhabditis elegans.
  1. Research: Theory, models and biology

    Wenying Shou et al.
    Theoretical ideas have a rich history in many areas of biology, and new theories and mathematical models have much to offer in the future.
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    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev et al.
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.
    1. Ecology
    2. Human Biology and Medicine

    Point of View: A transatlantic perspective on 20 emerging issues in biological engineering

    Bonnie C Wintle et al.
    Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.
    1. Neuroscience

    Rhythmogenic Networks: The ins and outs of breathing

    Jan-Marino Ramirez et al.
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    1. Neuroscience

    Integrative and distinctive coding of visual and conceptual object features in the ventral visual stream

    Chris B Martin et al.
    Perirhinal cortex, a brain structure located in the medial temporal lobe, uniquely supports the integration of visual and conceptual object information.
    1. Microbiology and Infectious Disease

    A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults

    Nguyen TH Mai et al.
    Adjunctive aspirin may reduce new brain infarcts and deaths in the first 60 days of treatment for HIV-uninfected adults with tuberculous meningitis.
    1. Neuroscience

    Neuropathological and transcriptomic characteristics of the aged brain

    Jeremy A Miller et al.
    High variability in neuropathology burden and interactions between dementia diagnosis and RNA quality present underappreciated complications when studying dementia in an aged population.
    1. Cell Biology
    2. Neuroscience

    Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release

    Zhao Xuan et al.
    Clarinet, a novel C. elegans active zone protein with homology to vertebrate Piccolo and Rim, uses its different isoforms for diverse functions, including synaptic vesicle clustering, vesicle release and synaptogenesis.

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